A gaseous signaling molecule hydrogen sulfide stimulates mitochondrial bioenergetics, maintains glutathione redox poise, and suppresses ROS to subvert viral rebound in latently infected CD4+ T cells from HIV subjects.
Comparative studies of gene expression in the uterus during pregnancy identifies new genes important for pregnancy and associated with complications such as preterm birth.
Circuit-wide calcium imaging during C. elegans foraging elucidates the functional architecture of a neural circuit controlling the choice between two alternative behavioral states.
Davide Cavalieri, Alexandra Angelova ... Rosa Cossart
Embryonic birthdate is a crucial determinant of heterogeneity among CA1 principal neurons, which include a previously overlooked subpopulation of pioneer neurons.
Activity levels in anterior and posterior cholinergic basal forebrain neurons are associated with distinct aspects of global brain state, sensory salience, reward expectation, and aversive reinforcement learning.
Rawan AlSubaie, Ryan WS Wee ... Andrew F MacAskill
Amygdala input to ventral hippocampus is both excitatory and inhibitory, and the balance of these two projections controls the formation of place preference via differential innervation of each hippocampal output population.
CapZ controls actin filament density around immature early endosomes via its C-terminal domain to facilitate the homotypic fusion of the endocytic vesicles, and it functions as a scaffold protein via its N-terminal domain to recruit RAB5 effectors to early endosomes.
