Browse our Research Articles

Page 604 of 1,424
    1. Cancer Biology

    Acid-base transporters and pH dynamics in human breast carcinomas predict proliferative activity, metastasis, and survival

    Nicolai J Toft, Trine V Axelsen ... Ebbe Boedtkjer
    Cellular acidity, capacity for net acid extrusion, and expression of acid-base transporters in human breast carcinomas independently predict variation in proliferative activity, lymph node metastasis, and patient survival.
    1. Microbiology and Infectious Disease
    2. Physics of Living Systems

    Crash landing of Vibrio cholerae by MSHA pili-assisted braking and anchoring in a viscoelastic environment

    Wenchao Zhang, Mei Luo ... Kun Zhao
    Mannose-sensitive hemagglutinin pili act as a braking and anchoring machine during the three-phase landing process of Vibrio cholerae.
    1. Neuroscience

    Insula to mPFC reciprocal connectivity differentially underlies novel taste neophobic response and learning in mice

    Haneen Kayyal, Sailendrakumar Kolatt Chandran ... Kobi Rosenblum
    aIC to mPFC connections are correlative and necessary both for taste novelty behavior and learning while the reciprocal connection from mPFC to aIC is correlative and necessary for novelty behavior.
    1. Computational and Systems Biology
    2. Stem Cells and Regenerative Medicine

    A deep learning algorithm to translate and classify cardiac electrophysiology

    Parya Aghasafari, Pei-Chi Yang ... Colleen E Clancy
    A deep learning network can classify cardiac myocytes into drug-free and drugged categories and predict the impact of electrophysiological perturbation across the continuum of aging.
    1. Genetics and Genomics

    Psychosocial experiences modulate asthma-associated genes through gene-environment interactions

    Justyna A Resztak, Allison K Farrell ... Francesca Luca
    Psychosocial environments modulate genetic risk of asthma and other allergic diseases through altered peripheral blood gene expression.
    1. Cell Biology
    2. Neuroscience

    Functional interdependence of the actin nucleator Cobl and Cobl-like in dendritic arbor development

    Maryam Izadi, Eric Seemann ... Michael M Kessels
    Extended biochemical and functional analyses in primary neurons show that early neuronal morphogenesis critically relies on cooperation of the actin nucleator Cobl and its ancestor Cobl-like and uncover their cooperative mechanisms at dendritic branch initiation sites.
    1. Computational and Systems Biology
    2. Developmental Biology

    Control of tissue development and cell diversity by cell cycle-dependent transcriptional filtering

    Maria Abou Chakra, Ruth Isserlin ... Gary D Bader
    A mathematical model predicts that cell cycle duration acts as a transcriptional filter and directly affects cell diversity in early eukaryotic development.
    1. Cancer Biology
    2. Chromosomes and Gene Expression

    Transcription-associated topoisomerase 2α (TOP2A) activity is a major effector of cytotoxicity induced by G-quadruplex ligands

    Madeleine Bossaert, Angélique Pipier ... Dennis Gomez
    Topoisomerase 2α DNA breaks induced by G-quadruplex ligands are associated with a topological stress resulting from a transcription-dependent mechanism and counteracted by DNA topoisomerase 1 and factors promoting transcription elongation.
    1. Cancer Biology
    2. Cell Biology

    Cavin3 released from caveolae interacts with BRCA1 to regulate the cellular stress response

    Kerrie-Ann McMahon, David A Stroud ... Robert G Parton
    Cavin3 associates with BRCA1 upon disassembly of caveolae in response to mechanical and non-mechanical stressors to influence DNA repair and apoptosis.
    1. Epidemiology and Global Health

    Relationship between changing malaria burden and low birth weight in sub-Saharan Africa: A difference-in-differences study via a pair-of-pairs approach

    Siyu Heng, Wendy P O'Meara ... Dylan S Small
    A novel pair-of-pairs matching approach finds that community-level reductions in malaria burden can potentially substantially reduce the low birth weight rate in sub-Saharan Africa, particularly among firstborns.