Browse our Research Articles

Page 621 of 1,423
    1. Neuroscience

    Unveiling the sensory and interneuronal pathways of the neuroendocrine connectome in Drosophila

    Sebastian Hückesfeld, Philipp Schlegel ... Michael J Pankratz
    Core of a neuroendocrine synaptic network consists of a parallel set of interneurons that target distinct combinations of neuroendocrine outputs, thus enabling variability and flexibility in selection of physiological activity.
    1. Neuroscience

    Differential dopaminergic modulation of spontaneous cortico–subthalamic activity in Parkinson’s disease

    Abhinav Sharma, Diego Vidaurre ... Esther Florin
    Dopaminergic medication has differential effects on the discovered electrophysiological networks, which could be used to develop new electrical and pharmacological interventions in Parkinson’s disease.
    1. Developmental Biology
    2. Stem Cells and Regenerative Medicine

    The critical role of Hedgehog-responsive mesenchymal progenitors in meniscus development and injury repair

    Yulong Wei, Hao Sun ... Ling Qin
    Meniscal Gli1+ cells are mesenchymal progenitors that contribute to the development and injury repair of meniscus.
    1. Cell Biology
    2. Immunology and Inflammation

    Multiplexed proteomics of autophagy-deficient murine macrophages reveals enhanced antimicrobial immunity via the oxidative stress response

    Timurs Maculins, Erik Verschueren ... Aditya Murthy
    Multiplexed mass spectrometry shows how the autophagy gene Atg16l1 regulates macrophage innate immunity against intracellular bacterial pathogens by modulating basal oxidative stress responses.
    1. Immunology and Inflammation
    2. Microbiology and Infectious Disease

    Reshaping of bacterial molecular hydrogen metabolism contributes to the outgrowth of commensal E. coli during gut inflammation

    Elizabeth R Hughes, Maria G Winter ... Sebastian E Winter
    Bioinformatics analyses and experiments in mouse models reveal how Escherichia coli accesses the molecular hydrogen pool to boost colonization during acute colitis.
    1. Neuroscience

    Cortical entrainment to hierarchical contextual rhythms recomposes dynamic attending in visual perception

    Peijun Yuan, Ruichen Hu ... Yi Jiang
    The human brain involuntarily exploits multiscale regularities in rhythmic contexts to recompose the dynamic profile of visual temporal attention.
    1. Cell Biology
    2. Neuroscience

    Short and long sleeping mutants reveal links between sleep and macroautophagy

    Joseph L Bedont, Hirofumi Toda ... Amita Sehgal
    Unbiased and targeted genetic approaches reveal a link between sleep and autophagy that could be relevant for sleep function, and for understanding pathological consequences of chronic sleep loss.
    1. Neuroscience

    Synaptic learning rules for sequence learning

    Eric Torsten Reifenstein, Ikhwan Bin Khalid, Richard Kempter
    Through mathematical analysis and computer simulations, the neuronal underpinnings of feasible models of sequence learning are delineated.
    1. Developmental Biology

    Abortive intussusceptive angiogenesis causes multi-cavernous vascular malformations

    Wenqing Li, Virginia Tran ... Mark H Ginsberg
    Genetic studies reveal that mosaic inactivation of ccm2 causes characteristic cerebral cavernous malformations in adult zebrafish and aberrant responses to blood flow that induce the formation of a lethal embryonic multi-cavernous venous malformation.
    1. Stem Cells and Regenerative Medicine

    HSPCs display within-family homogeneity in differentiation and proliferation despite population heterogeneity

    Tamar Tak, Giulio Prevedello ... Leïla Perié
    Hematopoietic stem and progenitor cells are heterogeneous on a population level, while cells derived from a common ancestor have similar division and differentiation patterns, indicating priming towards a certain differentiation/division fate.