Browse our Research Articles

Page 629 of 1,477
    1. Ecology
    2. Evolutionary Biology

    The evolution of strategy in bacterial warfare via the regulation of bacteriocins and antibiotics

    Rene Niehus, Nuno M Oliveira ... Kevin R Foster
    Evolutionary game theory identifies reciprocation as a key winning strategy for warring bacteria.
    1. Evolutionary Biology

    Ancient role of sulfakinin/cholecystokinin-type signalling in inhibitory regulation of feeding processes revealed in an echinoderm

    Ana B Tinoco, Antón Barreiro-Iglesias ... Maurice R Elphick
    Starfish feed by everting their stomach out of their mouth over prey and, interestingly, this unusual feeding mechanism is inhibited by substances similar to hormones that regulate feeding in humans.
    1. Neuroscience

    Separable neural signatures of confidence during perceptual decisions

    Tarryn Balsdon, Pascal Mamassian, Valentin Wyart
    Neural processes for perception and confidence can be separated thanks to computational electroencephalography, thus revealing a neural circuit specific to metacognition.
    1. Neuroscience

    Distributed functions of prefrontal and parietal cortices during sequential categorical decisions

    Yang Zhou, Matthew C Rosen ... David J Freedman
    Prefrontal cortex plays a leading role in sequential decisions compared to posterior parietal cortex and relies on nonlinear integration of sensory and mnemonic information for decision formation.
    1. Biochemistry and Chemical Biology
    2. Cell Biology

    β-hydroxybutyrate accumulates in the rat heart during low-flow ischaemia with implications for functional recovery

    Ross T Lindsay, Sophie Dieckmann ... Andrew J Murray
    β-Hydroxybutyrate accumulates in the perfused rat heart during ischaemia, driven by flux through both HMGCS and SCOT, with implications for functional recovery.
    1. Immunology and Inflammation

    ACLY ubiquitination by CUL3-KLHL25 induces the reprogramming of fatty acid metabolism to facilitate iTreg differentiation

    Miaomiao Tian, Fengqi Hao ... Min Wei
    Metabolic flux analysis, biochemistry assays, and functional confirmation in mice show that the ubiquitination and degradation of ATP-citrate lyase (ACLY) mediated by CUL3-KLHL25 promotes the switch from fatty acid synthesis to fatty acid oxidation for iTreg differentiation.
    1. Computational and Systems Biology
    2. Physics of Living Systems

    A simple regulatory architecture allows learning the statistical structure of a changing environment

    Stefan Landmann, Caroline M Holmes, Mikhail Tikhonov
    Minimal modifications of common regulatory circuits can allow bacteria to learn from the past to better predict the future, on a physiological, rather than evolutionary, timescale.
    1. Genetics and Genomics
    2. Immunology and Inflammation

    Evolution of cytokine production capacity in ancient and modern European populations

    Jorge Domínguez-Andrés, Yunus Kuijpers ... Mihai G Netea
    Neolithic was a turning point for immune responses in Europeans, favoring tolerance against intracellular pathogens, promoting inflammation against extracellular microbes, and being related to current auto-immune diseases.
    1. Neuroscience

    The severity of microstrokes depends on local vascular topology and baseline perfusion

    Franca Schmid, Giulia Conti ... Bruno Weber
    The number of inflows and outflows at the occluded capillary governs the local flow reduction, and the different topological configurations are probably designed for distinct functional tasks.
    1. Neuroscience

    Motor planning under uncertainty

    Laith Alhussein, Maurice A Smith
    New evidence shows that when there is uncertainty about an action's goal the motor system creates a single action plan that optimizes task performance rather than averaging multiple potential plans.