Inverse gradients of cell ingression and division in the epiblast allow the bipotent progenitors in the anterior streak to become the main progenitors for posterior axis formation from the tail bud.
Viktor J Radermacher, Vincent Fernandez ... Jonah N Choiniere
A new specimen of Heterodontosaurus elucidates how ornithischian dinosaurs evolved a body plan substantially different from that of other dinosaurs and what these differences meant for their breathing.
Akinobu Watanabe, Amy M Balanoff ... Mark A Norell
More integrated brains in crown birds evolved through a mosaic assembly of new evolutionary and developmental dynamics across neuroanatomical regions that occurred along the dinosaur-bird transition.
Mariena JA van der Plas, Jun Cai ... Artur Schmidtchen
Peptidomics method development and analysis of qualitative differences of peptide patterns in human wound fluids provide potential biomarkers for wound healing and infection.
Martina Dal Bello, Alfonso Pérez-Escudero ... Jeff Gore
Worms' attraction to pheromones turns into repulsion when a food patch is depleted, helping them avoid already exploited territories and search for new food sources.
A novel mathematical strategy for the integrated analysis of adult body structures quantifies the degree and nature of developmental robustness and its evolutionary implications.
Sharon R Stevens, Colleen M Longley ... Matthew N Rasband
Analysis of AnkyrinR conditional knockout mice shows that AnkyrinR regulates PV+ fast-spiking interneurons by organizing and maintaining perineuronal nets and through the membrane clustering of Kv3.1b K+ channels.
Brian D Alford, Eduardo Tassoni-Tsuchida ... Onn Brandman
A pooled genetic screening method measures the effect of knocking down every gene on a transcriptional stress response to proteotoxic stress (the heat shock response) using only nucleic acid sequencing, without cell enrichment or single-cell isolation.
