Browse our Research Articles

Page 631 of 1,392
    1. Cell Biology
    2. Immunology and Inflammation

    Anti-ferroptotic mechanism of IL4i1-mediated amino acid metabolism

    Leonie Zeitler, Alessandra Fiore ... Peter J Murray
    IL4i1 is an amino acid oxidase expressed in the mammalian immune system and snake venoms, which control diametrically opposite cell protection versus cell death pathways, respectively.
    1. Neuroscience

    Endoglycan plays a role in axon guidance by modulating cell adhesion

    Thomas Baeriswyl, Alexandre Dumoulin ... Esther T Stoeckli
    Endoglycan fine-tunes the interaction between guidance molecules and surface receptors during axon guidance and cell migration.
    1. Neuroscience

    Functional specialization within the inferior parietal lobes across cognitive domains

    Ole Numssen, Danilo Bzdok, Gesa Hartwigsen
    Data-driven and effective connectivity analyses reveal patterns of functional specialization, common mechanisms, and brain-wide interaction profiles within the human inferior parietal lobes for multiple functional domains.
    1. Developmental Biology
    2. Stem Cells and Regenerative Medicine

    Cystic proliferation of germline stem cells is necessary to reproductive success and normal mating behavior in medaka

    Luisa F Arias Padilla, Diana C Castañeda-Cortés ... Juan I Fernandino
    In medaka fish, the reduction of cystic proliferation of germ stem cells declines gametogenesis, reproduction success, and male sexual behavior, with a decrease of mating vigor.
    1. Physics of Living Systems

    Theory for the optimal detection of time-varying signals in cellular sensing systems

    Giulia Malaguti, Pieter Rein ten Wolde
    A theory is presented for the optimal design of cellular sensing systems that maximizes the sensing precision given resource constraints.
    1. Cell Biology
    2. Neuroscience

    TDP-43 maximizes nerve conduction velocity by repressing a cryptic exon for paranodal junction assembly in Schwann cells

    Kae-Jiun Chang, Ira Agrawal ... Jonah R Chan
    Glial TDP-43 regulates splicing and expression of neurofascin and is required for proper assembly and maintenance of paranodal axoglial junctions.
    1. Neuroscience

    Tonic firing mode of midbrain dopamine neurons continuously tracks reward values changing moment-by-moment

    Yawei Wang, Osamu Toyoshima ... Masayuki Matsumoto
    Although the phasic activity of midbrain dopamine neurons is known to represent reward values, these neurons displayed a tonic firing mode to continuously track reward values changing moment-by-moment.
    1. Neuroscience

    An optimized CRISPR/Cas9 approach for precise genome editing in neurons

    Huaqiang Fang, Alexei M Bygrave ... Richard L Huganir
    CRISPR/Cas9 based genomic editing for efficient endogenous protein tagging can be achieved by targeting non-coding sequences with two guides.
    1. Cell Biology
    2. Neuroscience

    Antagonistic roles for Ataxin-2 structured and disordered domains in RNP condensation

    Amanjot Singh, Joern Hulsmeier ... Baskar Bakthavachalu
    Ataxin-2 interacts with neuronal mRNA in RNP granules.
    1. Neuroscience

    C. elegans orthologs MUT-7/CeWRN-1 of Werner syndrome protein regulate neuronal plasticity

    Tsung-Yuan Hsu, Bo Zhang ... Bi-Tzen Juang
    The olfactory learning of Caenorhabditis elegans shows that the exonuclease and helicase domains of human Werner syndrome protein (WRN) coordinately regulate the biogenesis of small interfering RNAs to promote neuronal plasticity.