Browse our Research Articles

Page 635 of 1,477
    1. Neuroscience

    Gjd2b-mediated gap junctions promote glutamatergic synapse formation and dendritic elaboration in Purkinje neurons

    Sahana Sitaraman, Gnaneshwar Yadav ... Vatsala Thirumalai
    A protein that is a building block of intercellular bridges between neurons promotes their ability to grow dendrites and make synapses.
    1. Immunology and Inflammation

    HIF1α is required for NK cell metabolic adaptation during virus infection

    Francisco Victorino, Tarin M Bigley ... Wayne M Yokoyama
    During pathogen infection, natural killer cells require hypoxia-inducible factor-1α for optimal metabolism to prevent apoptosis, thereby reducing viral load and protecting against morbidity.
    1. Immunology and Inflammation
    2. Microbiology and Infectious Disease

    Integrated single-cell analysis unveils diverging immune features of COVID-19, influenza, and other community-acquired pneumonia

    Alex R Schuurman, Tom DY Reijnders ... Tom van der Poll
    Different etiologies of community-acquired pneumonia evoke both shared and diverging immunological responses.
    1. Plant Biology

    An oomycete effector subverts host vesicle trafficking to channel starvation-induced autophagy to the pathogen interface

    Pooja Pandey, Alexandre Y Leary ... Tolga O Bozkurt
    A pathogen effector mimics starvation-induced autophagy by subverting host endomembrane trafficking to stimulate biogenesis of autophagosomes around pathogen feeding sites, revealing how pathogens interlock distinct host compartments to facilitate infection.
    1. Neuroscience

    Physiological and motion signatures in static and time-varying functional connectivity and their subject identifiability

    Alba Xifra-Porxas, Michalis Kassinopoulos, Georgios D Mitsis
    BOLD fMRI fluctuations induced by head motion and variations in cardiac and breathing activity lead to artifactual patterns in functional connectivity as well as recurrent patterns in time-varying functional connectivity.
    1. Neuroscience

    Separable pupillary signatures of perception and action during perceptual multistability

    Jan W Brascamp, Gilles de Hollander ... Tomas Knapen
    When conscious visual perception changes, the observer's pupils simultaneously signal the accompanying change in visual cortical representation, and specific neuromodulatory activity that helps translate the altered visual experience into behavior.
    1. Cell Biology
    2. Developmental Biology

    Ciliary and extraciliary Gpr161 pools repress hedgehog signaling in a tissue-specific manner

    Sun-Hee Hwang, Bandarigoda N Somatilaka ... Saikat Mukhopadhyay
    Signaling specifically in cilia by a cAMP generating G-protein-coupled receptor directs tissue-specific morphogenesis.
    1. Neuroscience

    Cortical magnification in human visual cortex parallels task performance around the visual field

    Noah C Benson, Eline R Kupers ... Jonathan Winawer
    In humans, the surface area of early visual cortex across polar angle is distributed in a pattern that correlates strongly with radial asymmetries in behavioral performance on visual tasks.
    1. Computational and Systems Biology
    2. Physics of Living Systems

    Hypoxia triggers collective aerotactic migration in Dictyostelium discoideum

    Olivier Cochet-Escartin, Mete Demircigil ... Jean-Paul Rieu
    Cell assemblies can use environmental cues created by their own respiration, such as oxygen gradients, to collectively guide themselves to more favorable locations in a remarkably robust and long-lasting way.
    1. Developmental Biology

    Regulated delivery controls Drosophila Hedgehog, Wingless, and Decapentaplegic signaling

    Ryo Hatori, Brent M Wood ... Thomas B Kornberg
    Delivery of Hedgehog, Decapentaplegic and Wingless to target cells in the Drosophila wing imaginal disc is regulated in both amount and destination, and is not dependent on constitutive release or uptake from a common pool.