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Despite the known heme attachment motif (CXXCH) in all c-type cytochromes, attachment elements recognized by human and bacterial cytochrome c biogenesis pathways are distinct, providing clear targets for differential inhibitors.

Assessing plaque biomechanics by optical coherence tomography highlights the importance of the disrupting effects of plaque stress, bringing stress concentrations as the prime movers of plaque rupture back into clinical practice.

Signaling function of sigma 1 receptor is related to its ability to organize cholesterol-enriched microdomains in the endoplasmic reticulum membrane.

Calcineurin regulates an electrophysiological mechanism that activates the transcription of specific developmental genes in a heirarchical manner to scale fish appendages.

Elimination of GABA_A receptors from the axon terminals of specific retinal bipolar cell types alters the sensitivity and kinetics of retinal output.

Fate mapping analysis shows that not bona fide Langerhans cells but their ‘look-alikes’ dermal Langerhans cell-like cells migrate to the lymph nodes.

Behavioral and neural data converge in showing that medical experience reduces reactions to others' pain and distrust toward the target affects the processing of his feedback.

Action-value signals previously found in many brain areas can be accounted for neither by concurrent serial correlations in neural activity and action value nor by signals for other decision variables.

In cooperatively breeding Damaraland mole-rats, transitioning to 'queen' results in extensive gene regulatory and morphological remodeling, but also costs to skeletal integrity that scale with reproductive investment.

FOXM1 is co-expressed with its bidirectional gene partner RHNO1, and the two genes promote DNA repair, cell growth and survival, and chemotherapy resistance in ovarian cancer.