Browse our Research Articles

Page 634 of 1,392
    1. Genetics and Genomics
    2. Neuroscience

    Mayday sustains trans-synaptic BMP signaling required for synaptic maintenance with age

    Jessica M Sidisky, Daniel Weaver ... Daniel Babcock
    Maintaining synaptic structure and function over time requires continuous signaling from pathways that are crucial for synapse development.
    1. Developmental Biology

    Retrograde ERK activation waves drive base-to-apex multicellular flow in murine cochlear duct morphogenesis

    Mamoru Ishii, Tomoko Tateya ... Tsuyoshi Hirashima
    Live-cell imaging and mathematical modeling reveal the physical basis of collective cell migration underlying spiral cochlear duct formation during murine inner ear development.
    1. Evolutionary Biology
    2. Genetics and Genomics

    Emergence and diversification of a highly invasive chestnut pathogen lineage across southeastern Europe

    Lea Stauber, Thomas Badet ... Daniel Croll
    The chestnut blight fungus has successfully established an intermediary, diverse European bridgehead population, giving rise to a highly invasive clonal lineage spreading across southeastern Europe.
    1. Developmental Biology
    2. Evolutionary Biology

    Developmental hourglass and heterochronic shifts in fin and limb development

    Koh Onimaru, Kaori Tatsumi ... Shigehiro Kuraku
    Omics approaches reveal conserved and diversified gene regulation between fin and limb development.
    1. Biochemistry and Chemical Biology
    2. Structural Biology and Molecular Biophysics

    SARS-CoV-2 S protein:ACE2 interaction reveals novel allosteric targets

    Palur V Raghuvamsi, Nikhil K Tulsian ... Ganesh S Anand
    SARS-CoV-2 spike protein binding to receptor angiotensin-converting enzyme 2 allosterically enhances furin proteolysis at distal S1/S2 cleavage sites.
    1. Neuroscience

    Drosophila uses a tripod gait across all walking speeds, and the geometry of the tripod is important for speed control

    Chanwoo Chun, Tirthabir Biswas, Vikas Bhandawat
    Drosophila uses a gait close to the tripod throughout its speed range, and changes in speed are accompanied by changes in the geometry of the tripod.
    1. Chromosomes and Gene Expression

    Cohesin architecture and clustering in vivo

    Siheng Xiang, Douglas Koshland
    Cohesin adopts a flexible butterfly conformation in vivo and forms spatial and temporal regulated ordered clusters to maintain cohesion and condensation.
    1. Developmental Biology

    EKLF/KLF1 expression defines a unique macrophage subset during mouse erythropoiesis

    Kaustav Mukherjee, Li Xue ... James J Bieker
    Mouse fetal liver macrophages that support erythroid differentiation within erythroblastic islands exhibit a unique and transient expression signature under transcriptional control of EKLF/KLF1.
    1. Biochemistry and Chemical Biology
    2. Neuroscience

    Phasic oxygen dynamics confounds fast choline-sensitive biosensor signals in the brain of behaving rodents

    Ricardo M Santos, Anton Sirota
    Fast fluctuations of oxygen, linked to behavioral and neural dynamics in vivo, cause phasic transients is amperometry-measured cholinergic signals via the mechanism of non-steady-state enzyme kinetics in the choline-oxidase-based biosensor.
    1. Cell Biology
    2. Physics of Living Systems

    Non-genetic inheritance restraint of cell-to-cell variation

    Harsh Vashistha, Maryam Kohram, Hanna Salman
    Quantitative measurement of epigenetic memory and inheritance dynamics.