eIF2-P activates the integrated stress response by inducing a conformational change in eIF2B that decreases substrate (eIF2) binding and reduces eIF2B's catalytic activity.
Hannah C Goldbach, Bradley Akitake ... Mark H Histed
In a simple visual task, that in principle could be performed using information in V1 alone, perturbations of secondary visual areas impair perception.
The regulation of sympathetic innervation density by beige adipocytes in subcutaneous fat is important during a critical developmental window, but dispensable during adulthood.
Properties of various microbial communities time series, such as the noise color and neutrality, are captured by stochastic generalized Lotka-Volterra equations, even in the absence of interactions.
Model-based fMRI reveals the neurocomputational bases of accepting a bribe when power-holders consider two moral costs, conniving with a fraudulent briber and the harm brought to a third party.
SABRE, which is present in a wide range of eukaryotes, localizes to ER subdomains in plants, impacting cell expansion and callose deposition during cell plate maturation.
Two-photon in vivo calcium imaging reveals short time-scale, synchronous and sparse population activity in dentate gyrus that replays place-related information, and is important for formation of dentate-dependent spatial memory.
Oligodendrocytes with an enhanced ability to withstand cytotoxic stress display an increased capacity to remyelinate demyelination lesions of the CNS in the presence of an inflammatory environment.
