Browse our Research Articles

Page 697 of 1,423
    1. Microbiology and Infectious Disease
    2. Structural Biology and Molecular Biophysics

    Molecular rationale for antibody-mediated targeting of the hantavirus fusion glycoprotein

    Ilona Rissanen, Robert Stass ... Thomas A Bowden
    An integrated cryoEM and X-ray crystallography study resolves the structural basis for antibody-mediated targeting of the hantavirus fusion glycoprotein and provides insight into the conformational landscape of the hantavirion surface.
    1. Biochemistry and Chemical Biology
    2. Structural Biology and Molecular Biophysics

    In vitro reconstitution of dynamically interacting integral membrane subunits of energy-coupling factor transporters

    Inda Setyawati, Weronika K Stanek ... Dirk J Slotboom
    Integral membrane subunits of energy-coupling factor transporters associate with and dissociate from each other as part of the transport mechanism.
    1. Neuroscience

    Diffusion-MRI-based regional cortical microstructure at birth for predicting neurodevelopmental outcomes of 2-year-olds

    Minhui Ouyang, Qinmu Peng ... Hao Huang
    Diffusion-MRI-based cerebral cortical microstructure encoding regionally differential dendritic arborization and synaptic formation at birth robustly predicts future 2-year-old cognitive and language outcomes with regionally heterogeneous contribution that exhibits functional selectivity.
    1. Evolutionary Biology

    Adaptive evolution of an essential telomere protein restricts telomeric retrotransposons

    Bastien Saint-Leandre, Courtney Christopher, Mia T Levine
    Evolution strictly preserves telomere stability but rapidly diversifies telomere length regulation in Drosophila.
    1. Neuroscience

    Impaired adaptation of learning to contingency volatility in internalizing psychopathology

    Christopher Gagne, Ondrej Zika ... Sonia J Bishop
    Hierarchical modeling of internalizing symptoms and task performance reveals that difficulty adapting probabilistic learning to second-order uncertainty is common to anxiety and depression and holds across rewarding and punishing outcomes.
    1. Neuroscience

    Central processing of leg proprioception in Drosophila

    Sweta Agrawal, Evyn S Dickinson ... John C Tuthill
    Proprioceptive signals about leg position, movement, and vibration are integrated in downstream circuits in the fly's central nervous system.
    1. Neuroscience

    Reconstruction of natural images from responses of primate retinal ganglion cells

    Nora Brackbill, Colleen Rhoades ... EJ Chichilnisky
    The visual message conveyed by retinal neurons to the brain when signaling natural scenes resembles the individual receptive fields only when viewed in context of the neuronal population.
    1. Medicine

    Vanishing white matter disease expression of truncated EIF2B5 activates induced stress response

    Matthew D Keefe, Haille E Soderholm ... Joshua L Bonkowsky
    Neurological pathology and chronic activation of the induced stress response are caused by expression of a truncated EIF2B5 in vanishing white matter disease.
    1. Genetics and Genomics

    Drosophila PDGF/VEGF signaling from muscles to hepatocyte-like cells protects against obesity

    Arpan C Ghosh, Sudhir Gopal Tattikota ... Norbert Perrimon
    A muscle-derived signaling molecule suppresses excessive accumulation of lipids in the Drosophila adipose tissue by activating the Pi3K/Akt/mTOR signaling cascade in the Drosophila hepatocyte-like cells.
    1. Cell Biology

    Conformation of the nuclear pore in living cells is modulated by transport state

    Joan Pulupa, Harriet Prior ... Sanford M Simon
    Polarized fluorescence microscopy of individual nuclear pores in vivo reveals conformational changes in select domains of proteins of the inner ring.