Elizabeth B Draganova, Jiayan Zhang ... Ekaterina E Heldwein
Interactions were visualized between the nuclear egress complex from herpes simplex virus and a capsid protein that could promote nucleocytoplasmic translocation of the capsid in infected cells.
Depletion of the mechanosensitive ion channel PEZO-1 in C. elegans disrupts the sheath and spermathecae cells to disrupt oocyte ovulation, resulting in crushed oocytes.
The loss of lamination in mammalian brain structures under cellular heterotopia carries with it non-uniform ramifications for the various components of the canonical CA1 microcircuitry.
Experimental results in Drosophila support a model in which gene expression is fundamentally controlled by morphogens tuning the same transcription parameter for genes that are expressed in highly diverse patterns.
Abril Angélica Escamilla-Ayala, Ragna Sannerud ... Wim Annaert
Super-resolution microscopy sets a new strategy to comprehend the membrane organization of γ-secretase at single complex resolution identifying nanodomain associations and its diffusion in situ in the living membrane.
Prevention and antivenom treatment could reduce snakebite deaths, which killed 1.2 million Indians from 2000-2019, about 70% of which occurred in eight states, and half during four rainy months.
Human NK cells engineered to express a PD-L1 chimeric antigen receptor can control murine and human tumors and reduce myeloid cells expressing high levels of PD-L1.
In yeast, a fluorescent vacuolar cargo departs from Golgi cisternae early in the TGN stage of maturation, and traffic from prevacuolar endosomes to the vacuole apparently involves a kiss-and-run mechanism.
