S-type anion channel activity, which promotes stomatal closure and improves anti-fungal immunity in plants, is directly regulated through phosphorylation by a kinase of the chitin receptor complex.
Míriam Javier-Torrent, Sergi Marco ... Carlos A Saura
EphA signaling plays dual opposite roles on axon dynamics in neurons, so it inhibits and promotes axon growth through ligand binding and receptor processing, respectively.
The rate of DNA unwinding by RecQ helicases is dramatically modulated by the DNA duplex stability in a geometry-dependent manner, providing an intrinsic mechanism for suppressing illegitimate recombination.
Male and female Drosophila share core metabolic responses to different nutritional environments, but show opposing patterns of nutrient-dependent reproductive regulation.
Heme accumulation is toxic, but deficiency of the heme transporter HRG1/SLC48A1 causes heme sequestration and crystallization into hemozoin within enlarged lysosomes of macrophages, thereby conferring heme tolerance to mammals.
Ramakrishnan Vasudeva, Andreas Sutter ... Matthew JG Gage
Sperm and egg development are temperature sensitive, enabling males and females to significantly improve their reproductive success by matching gamete function to varying thermal environments for fertilisation and offspring development.
Impairment of the autocrine S1PR1-Gi signaling on HEVs results in high-endothelial cell apoptosis, reduced CCL21-secretion from HEVs, and cessation of HEV-DC interactions and lymphocyte immigration across the high-endothelial barrier.
Environmental transmission is atypical of symbionts that have undergone genome degradation, yet genetically reduced deep-sea anglerfish symbionts likely persist in the deep sea biome in search of a new host.
