Browse our Research Articles

Page 945 of 1,383
    1. Biochemistry and Chemical Biology
    2. Plant Biology

    Effects of microcompartmentation on flux distribution and metabolic pools in Chlamydomonas reinhardtii chloroplasts

    Anika Küken, Frederik Sommer ... Tabea Mettler-Altmann
    Mathematical models reveal that under the physiologically different conditions ambient and high CO2, two algal microcompartments are metabolically connected by facilitated transport.
    1. Evolutionary Biology
    2. Neuroscience

    Recalibrating timing behavior via expected covariance between temporal cues

    Benjamin J De Corte, Rebecca R Della Valle, Matthew S Matell
    Rats act as if they expect that the delays associated with temporal cues will covary due to a common causal factor.
    1. Cell Biology
    2. Developmental Biology

    Shear-induced damped oscillations in an epithelium depend on actomyosin contraction and E-cadherin cell adhesion

    Ehsan Sadeghipour, Miguel A Garcia ... Beth L Pruitt
    Cell movement toward and away from the midline of an epithelium over tens of hours are caused by spontaneous or externally-applied shear forces to eliminate force imbalances within the tissue.
    1. Neuroscience

    Dynamic neuromuscular remodeling precedes motor-unit loss in a mouse model of ALS

    Éric Martineau, Adriana Di Polo ... Richard Robitaille
    Motor axons undergo dynamic branch-specific changes for weeks before complete neuronal degeneration in a model of amyotrophic lateral sclerosis, highlighting the importance of peripheral factors, intrinsic and extrinsic to motoneurons.
    1. Microbiology and Infectious Disease

    Chromatin mapping identifies BasR, a key regulator of bacteria-triggered production of fungal secondary metabolites

    Juliane Fischer, Sebastian Y Müller ... Axel A Brakhage
    Genome-wide chromatin mapping during bacterial-fungal cocultivation identifies the Myb-like transcription factor BasR as the major regulatory node of bacteria-triggered production of fungal secondary metabolites.
    1. Developmental Biology
    2. Stem Cells and Regenerative Medicine

    WNT signaling memory is required for ACTIVIN to function as a morphogen in human gastruloids

    Anna Yoney, Fred Etoc ... Ali H Brivanlou
    The requirement for WNT signaling in mesendoderm differentiation is temporally separate from that of ACTIVIN signaling and acts to switch the output of ACTIVIN/SMAD2 from pluripotency maintenance to mesendoderm patterning.
    1. Cancer Biology
    2. Chromosomes and Gene Expression

    Multiple tumor suppressors regulate a HIF-dependent negative feedback loop via ISGF3 in human clear cell renal cancer

    Lili Liao, Zongzhi Z Liu ... Haifeng Yang
    Major secondary tumor suppressors in kidney cancer are required to maintain the activity of a tumor suppressive transcription factor after the loss of the primary tumor suppressor VHL.
    1. Microbiology and Infectious Disease
    2. Structural Biology and Molecular Biophysics

    Epitope resurfacing on dengue virus-like particle vaccine preparation to induce broad neutralizing antibody

    Wen-Fan Shen, Jedhan Ucat Galula ... Day-Yu Chao
    Despite size heterogeneity, an epitope-resurfaced mature-form dengue VLP has the potential to induce quaternary structure-recognizing broad cross-reactive neutralizing antibodies.
    1. Neuroscience

    Multiple neurons encode CrebB dependent appetitive long-term memory in the mushroom body circuit

    Yves F Widmer, Cornelia Fritsch ... Simon G Sprecher
    The transcription factor CrebB mediates long-term memory formation in different neurons within the mushroom body learning circuit, including mushroom body intrinsic and output neurons but not dopaminergic input neurons.
    1. Cell Biology

    Bid maintains mitochondrial cristae structure and function and protects against cardiac disease in an integrative genomics study

    Christi T Salisbury-Ruf, Clinton C Bertram ... Sandra S Zinkel
    An integrative approach, combining genetic mouse and large-scale human genetics studies, was used to reveal a novel role for the Bcl-2 protein Bid in maintenance of mitochondrial function that alters susceptibility to myocardial infarction.