Variation in the rate of mixed infections by malaria parasites and the relatedness structure among infecting strains reveals diversity in local epidemiological processes.
A simple and effective method facilitates the study of in vivo transcriptional dynamics using transcriptional enhancers and destabilized fluorescent protein, which is suitable for both live imaging and fixed studies.
Alison K Gillingham, Jessie Bertram ... Sean Munro
Relocation of Rab, Ras and Rho family GTPases to the surface of mitochondria enables efficient identification of their effectors, exchange factors and GAPs by proximity biotinylation.
Katherine G Zyner, Darcie S Mulhearn ... Shankar Balasubramanian
For the first time, the spectrum of genes and pathways interacting with alternative DNA structures called G-quadruplexes in humans is revealed highlighting new possibilities for the pursuit of cancer therapies.
A series of genetically-encoded fluorescent reporters that allow imaging of neuropeptide release in vivo, with sub-second temporal and nerve terminal-level spatial resolution are developed.