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Page 133 of 1,782
    1. Developmental Biology
    2. Genetics and Genomics

    Computer prediction and genetic analysis identifies retinoic acid modulation as a driver of conserved longevity pathways in genetically-diverse Caenorhabditis nematodes

    Stephen A Banse, Christine A Sedore ... Patrick C Phillips
    Not revised
    Reviewed Preprint v1
    • Important
    • Compelling
    1. Cell Biology
    2. Microbiology and Infectious Disease

    Decoding the biogenesis of HIV-induced CPSF6 puncta and their fusion with the nuclear speckle

    Chiara Tomasini, Celine Cuche ... Francesca Di Nunzio
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Incomplete
    1. Neuroscience

    Diverse calcium dynamics underlie place field formation in hippocampal CA1 pyramidal cells

    Mate Sumegi, Gaspar Olah ... Zoltan Nusser
    Not revised
    Reviewed Preprint v1
    • Important
    • Solid
    • Incomplete
    1. Epidemiology and Global Health

    Predicting the causal relationship between polyunsaturated fatty acids and cerebral aneurysm risk from a Mendelian randomization study

    Weijie Yu, Liwei Zhou ... Zhanxiang Wang
    Revised
    Reviewed Preprint v2
    Updated
    • Useful
    • Solid
    1. Evolutionary Biology

    On the nature of the earliest known lifeforms

    Dheeraj Kanaparthi, Frances Westall ... Tillmann Lueders
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Solid
    1. Neuroscience
    2. Computational and Systems Biology

    Self-association enhances early attentional selection through automatic prioritization of socially salient signals

    Meike Scheller, Jan Tünnermann ... Jie Sui
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Solid
    1. Neuroscience

    Human Brain Ancestral Barcodes

    Darryl Shibata
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Incomplete
    1. Neuroscience

    Neural adaptation to the eye’s optics through phase compensation

    Antoine Barbot, John T Pirog ... Geunyoung Yoon
    Not revised
    Reviewed Preprint v1
    • Important
    • Convincing
    1. Biochemistry and Chemical Biology

    Target protein identification in live cells and organisms with a non-diffusive proximity tagging system

    Yingjie Sun, Changheng Li ... Youngnam N Jin
    Pup-On-target for Small molecule Target Identification Technology, POST-IT, is a revolutionary tool for accurately identifying protein targets of bioactive molecules in living cells and organisms, successfully identifying SEPHS2 and VPS37C as targets for dasatinib and hydroxychloroquine, respectively.
    1. Neuroscience

    Three-dimensional single-cell transcriptome imaging of thick tissues

    Rongxin Fang, Aaron Halpern ... Xiaowei Zhuang
    By integrating multiplexed error-robust fluorescence in situ hybridization (MERFISH), deep learning, optical sectioning, and protocol optimization, thick-tissue 3D MERFISH allows volumetric single-cell transcriptome imaging of thick-tissue samples, broadening the scope of applications of spatial genomics.
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