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    1. Neuroscience

    A ‘double-edged’ role for type-5 metabotropic glutamate receptors in pain disclosed by light-sensitive drugs

    Serena Notartomaso, Nico Antenucci ... Volker Neugebauer
    Photopharmacological manipulations of mGlu5 receptors with light-sensitive negative allosteric modulators show brain region-specific roles in pain modulation and suggest that blockade of mGlu5 receptors in the amygdala may limit the overall analgesic activity of mGlu5 receptor antagonists.
    1. Cell Biology
    2. Developmental Biology

    H2A.Z deposition at meiotic prophase I underlies homologous recombination and pachytene genome activation during male meiosis

    Shenfei Sun, Yamei Jiang ... Xinhua Lin
    Not revised
    Reviewed Preprint v1
    • Important
    • Solid
    1. Neuroscience

    Brain-wide arousal signals are segregated from movement planning in the superior colliculus

    Richard Johnston, Matthew A Smith
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Incomplete
    1. Developmental Biology
    2. Genetics and Genomics

    sisterless A is required for activation of Sex lethal in the Drosophila germline

    Raghav Goyal, Ellen Baxter, Mark Van Doren
    Not revised
    Reviewed Preprint v1
    • Useful
    • Convincing
    • Incomplete
    1. Cell Biology

    SARS-CoV-2 NSP13 interacts with TEAD to suppress Hippo-YAP signaling

    Fansen Meng, Jong Hwan Kim ... James F Martin
    Not revised
    Reviewed Preprint v1
    • Important
    • Solid
    1. Neuroscience

    Cone bipolar cell synapses generate transient versus sustained signals in parallel ON pathways of the mouse retina

    Sidney P Kuo, Wan-Qing Yu ... Fred Rieke
    Not revised
    Reviewed Preprint v1
    • Important
    • Solid
    1. Neuroscience

    An applicable and efficient retrograde monosynaptic circuit mapping tool for larval zebrafish

    Tian-Lun Chen, Qiu-Sui Deng ... Xu-Fei Du
    Not revised
    Reviewed Preprint v1
    • Important
    • Solid
    1. Ecology

    Near infrared radiation-driven oxygenic photosynthesis contributes substantially to primary production in biofilms harboring chlorophyll f-containing cyanobacteria

    Maria Mosshammer, Erik CL Trampe ... Michael Kühl
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
    1. Neuroscience

    Accelerated spike-triggered non-negative matrix factorization reveals coordinated ganglion cell subunit mosaics in the primate retina

    Sören J Zapp, Mohammad H Khani ... Tim Gollisch
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Convincing
    1. Developmental Biology

    FBXO24 deletion causes abnormal accumulation of membraneless electron-dense granules in sperm flagella and male infertility

    Yuki Kaneda, Haruhiko Miyata ... Masahito Ikawa
    FBXO24, a testis-enriched E3 ubiquitin ligase, is essential for sperm flagellum formation and male fertility in mice.
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