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Experimental results and computational modeling reveal many factors that influence if a gene can be efficiently silenced using RNA interference.

Bacteria release ATP as part of their attack in sepsis.

Elucidating the 1-naphthylamine degradation pathway in Pseudomonas sp. strain JS3066 and analyzing the catalytic mechanism of the 1-naphthylamine glutamine synthetase deepens the understanding of microbial degradation of polycyclic aromatic amines.

Transient platelet accumulation supports oligodendrocyte progenitor cell differentiation during myelin repair, while sustained exposure to elevated platelet numbers hampers the generation of remyelinating cells.

The generation of phosphoinositide 3,4,5-trisphosphate causes an increase in the number of TRPV1 ion channels and insulin receptors in the plasma membrane.

The SEL-5/AAK1 kinase unexpectedly influences Wnt signalling-dependent processes in a multicellular organism without using its enzymatic activity.

Anatomical study reveals a new perspective on the definition of an electrical synapse where, in addition to the communicating role of gap junctions, additional cellular structures might be involved in the support and regulation of these intercellular channels.

Non-duplex DNA structures induce distant chromatin-chromatin interactions and gene activation over long distances.