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Page 283 of 1,782
    1. Neuroscience

    Conditional chemoconnectomics (cCCTomics) as a strategy for efficient and conditional targeting of chemical transmission

    Renbo Mao, Jianjun Yu ... Yi Rao
    New toolkits have been developed to enable cell-type-specific manipulation of CCT genes with remarkable efficiency while also uncovering the role of CNMa signal in regulating morning anticipation.
    1. Neuroscience

    Neural representations of predicted events: Evidence from time-resolved EEG decoding

    Ai-Su Li, Jan Theeuwes, Dirk van Moorselaar
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Incomplete
    1. Computational and Systems Biology
    2. Physics of Living Systems

    Development of equation of motion deciphering locomotion including omega turns of Caenorhabditis elegans

    Taegon Chung, Iksoo Chang, Sangyeol Kim
    ElegansBot, a two-dimensional rigid body chain model, simulates various locomotion of C. elegans, including omega and delta turns, using Newtonian equations of motion.
    1. Neuroscience

    A new ‘CFS tracking’ paradigm reveals uniform suppression depth regardless of target complexity or salience

    David Alais, Jacob Coorey ... Matthew J Davidson
    A new and efficient continuous flash suppression (CFS) method is presented that provides breakthrough and suppression thresholds to quantify depth of target suppression.
    1. Cancer Biology
    2. Chromosomes and Gene Expression

    Ribosome subunit attrition and activation of the p53–MDM4 axis dominate the response of MLL-rearranged cancer cells to WDR5 WIN site inhibition

    Gregory Caleb Howard, Jing Wang ... William P Tansey
    Analysis of the action of WDR5 inhibitors in leukemia cells reveals decreased ribosome inventory, impaired protein synthesis, induction of nucleolar stress, and activation of p53 via alternative splicing of MDM4.
    1. Cancer Biology
    2. Cell Biology

    N-cadherin directs the collective Schwann cell migration required for nerve regeneration through Slit2/3-mediated contact inhibition of locomotion

    Julian JA Hoving, Elizabeth Harford-Wright ... Alison C Lloyd
    N-cadherin and Slit2/3/Robo interactions provide the outward force to drive collective Schwann cell migration during nerve regeneration, identifying a dual role for N-cadherin in both adhesion and repulsion processes during Schwann cell collective migration.
    1. Genetics and Genomics

    Khdc3 Regulates Metabolism Across Generations in a DNA-Independent Manner

    Liana Senaldi, Nora Hassan ... Matthew Smith-Raska
    Not revised
    Reviewed Preprint v1
    • Important
    • Incomplete
    1. Plant Biology

    A shade-responsive microProtein in the Arabidopsis ATHB2 gene regulates elongation growth and root development

    Ashleigh Edwards, Maurizio Junior Chiurazzi ... Stephan Wenkel
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Incomplete
    1. Developmental Biology
    2. Structural Biology and Molecular Biophysics

    Deep learning insights into the architecture of the mammalian egg-sperm fusion synapse

    Arne Elofsson, Ling Han ... Luca Jovine
    AlphaFold-Multimer was used to investigate extracellular protein interactions involved in mammalian egg-sperm recognition, suggesting a putative pentameric complex that includes TMEM81, a sperm protein not previously involved in gamete recognition.
    1. Ecology
    2. Evolutionary Biology

    Evolutionary trade-offs in dormancy phenology

    Théo Constant, F Stephen Dobson ... Sylvain Giroud
    Dormancy during non-life-threatening periods that are unfavorable for reproduction may be more widespread than previously appreciated.