Cell Biology

Latest articles

1. 1. Cell Biology

   Cytoplasmic circular dsDNA is a key constituent of stress granules

   Natalia A Demeshkina, Adrian R Ferré-D'Amaré

   Extrachromosomal circular DNA has been identified as a novel component of stress granule cores, indicating its essential involvement in eukaryotic stress response pathways at the level of protein synthesis.
2. 1. Cell Biology
   2. Chromosomes and Gene Expression

   A genetic toolkit for stable transgenesis in the anaerobic gut parasite Blastocystis ST7-B

   M Rey Toleco, Kevin SW Tan, Mark van der Giezen
3. 1. Cell Biology

   The cell cycle variant in multiciliated cells incorporates 2 centriole biogenesis cycles

   Amélie-Rose Boudjema, Rémi Balagué ... Alice Meunier
4. 1. Cell Biology
   2. Microbiology and Infectious Disease

   Cell cycle dependent variation in endocytosis drives phenotypic diversity in M. tuberculosis

   Neeraja Subhash, Sandhya Krishnan Radhakrishnan ... Varadharajan Sundaramurthy
5. 1. Cell Biology
   2. Neuroscience

   Stable excitatory-inhibitory synapse balance despite dynamic turnover

   Krassimira A Garbett, James P Allen ... Richard C Sando
6. 1. Cell Biology

   Proteomic composition and mutual assembly of the C2a projection in vertebrate motile cilia

   Qian Lyu, Qingchao Li ... Huijie Zhao

   Deficiency in any of the interdependent C2a proteins (CCDC108, MYCBPAP, and CFAP70) collapses this central pair microtubule-associated projection, disrupting vertebrate ciliary movement, and causing primary ciliary dyskinesia phenotypes in mice.
7. 1. Cell Biology
   2. Microbiology and Infectious Disease

   Canonical and phosphoribosyl ubiquitination coordinate to stabilize a proteinaceous structure surrounding the Legionella-containing vacuole

   Adriana Steinbach, Chetan Mokkapati ... Shaeri Mukherjee

   Two families of ubiquitin ligases secreted by the intracellular pathogen Legionella pneumophila utilize distinct chemistries to form a stable, ubiquitin-rich structure around the vacuole, which is subsequently disassembled as infection progresses.
8. 1. Cell Biology
   2. Physics of Living Systems

   Sarcomere dynamic instability and stochastic heterogeneity drive robust cardiomyocyte contraction

   Daniel Haertter, Lara Hauke ... Christoph F Schmidt
9. 1. Cell Biology
   2. Genetics and Genomics

   Cytosolic Carboxypeptidase 5 maintains mammalian ependymal multicilia to ensure proper homeostasis and functions of the brain

   Rubina Dad, Yujuan Wang ... Hui-Yuan Wu
10. 1. Cell Biology
    2. Genetics and Genomics

    Mechanistic insights into transcriptional regulation of ARHGAP36 expression identify a factor predictive of neuroblastoma survival

    Serhiy Havrylov, Armin M Gamper, Ordan J Lehmann

    Genetic experiments integrated with ChIP-sequencing and CRISPR interference reveal that overexpression of Foxc1 transcriptionally activates the expression of Arhgap36 and dysregulates multiple facets of Hedgehog pathway activity.