Cell Biology

Latest articles

1. 1. Cell Biology
   2. Structural Biology and Molecular Biophysics

   Unbend, correction of local beam-induced sample motion in cryo-EM images using a 3D spline model

   Lingli Kong, Ximena Zottig ... Nikolaus Grigorieff

   Movie alignment software uses a 3D spline model to capture beam-induced motion in cryo-electron microscopy movie frames, correct local sample distortions, and improve two-dimensional template matching signal-to-noise ratios in the corrected images.
2. 1. Cell Biology

   The FAM53C/DYRK1A axis regulates the G1/S transition of the cell cycle

   Taylar Hammond, Jong Bin Choi ... Julien Sage

   The poorly characterized FAM53C protein is an inhibitor of the DYRK1A kinase and governs the G1/S transition of the cell cycle.
3. 1. Cell Biology
   2. Developmental Biology

   Prickle and Ror modulate Dishevelled-Vangl interaction to regulate non-canonical Wnt signaling during convergent extension in Xenopus

   Hwa-seon Seo, Deli Yu ... Jianbo Wang

   During convergent extension morphogenesis, non-canonical Wnt induces the signal transducer Dishevelled to transition from Vangl to Frizzled, a process that is inhibited by Prickle but facilitated by the co-receptor Ror.
4. 1. Cell Biology

   Single-cell lineage tracing identifies hemogenic endothelial cells in the adult mouse bone marrow

   Jing-Xin Feng, Mei-Ting Yang ... Giovanna Tosato

   Single-cell and bulk lineage tracing reveals that adult bone marrow endothelial cells generate functional hematopoietic progenitor and mature blood cells, expanding the cell sources of postnatal hematopoiesis.
5. 1. Cell Biology

   Ubiquitin Ligase ITCH Regulates Life Cycle of SARS-CoV-2 Virus

   Qiwang Xiang, Camille Wouters ... Jiou Wang
6. 1. Cell Biology
   2. Immunology and Inflammation

   Clathrin-independent endocytosis and retrograde transport in cancer cells tune immune synapse organization and CD8 T cell response

   Shiqiang Xu, Alix Buridant ... Henri-François Renard

   Endophilin-A3-mediated clathrin-independent endocytosis and retrograde trafficking in cancer cells regulate ICAM1 organization at the immune synapse and influence cytotoxic CD8 T cell response.
7. 1. Cell Biology
   2. Developmental Biology

   Zinc is a Key Regulator of the Sperm-Specific K⁺ Channel (Slo3) Function

   Rizki Tsari Andriani, Tanadet Pipatpolkai ... Takafumi Kawai
8. 1. Cell Biology
   2. Genetics and Genomics

   Mechanistic insights into transcriptional regulation of ARHGAP36 expression identify a factor predictive of neuroblastoma survival

   Serhiy Havrylov, Armin M Gamper, Ordan J Lehmann
9. 1. Cell Biology

   Prior cocaine use disrupts identification of hidden states by single units and neural ensembles in orbitofrontal cortex

   Wenhui Zong, Lauren Mueller ... Geoffrey Schoenbaum

   Rats with a history of cocaine use exhibited prolonged encoding of idiosyncratic task features in orbitofrontal cortex and a reduced ability to compress such features to identify underlying hidden states.
10. 1. Cell Biology

    Orderly mitosis shapes interphase genome architecture

    Krishnendu Guin, Adib Keikhosravi ... Tom Misteli

    High-throughput CRISPR-KO imaging screens reveal that disruption of mitotic processes impairs spatial genome organization in daughter cells.