Cell Biology

Cell Biology

eLife reviews research spanning vesicle transport and signal transduction to cell cycle and cell polarity and fate. Learn more about what we review and sign up for the latest content.
Illustration by Davide Bonazzi

Latest articles

    1. Cell Biology
    2. Neuroscience

    FMRP regulates neuronal RNA granules containing stalled ribosomes, not where ribosomes stall

    Jewel T-Y Li, Mehdi Amiri ... Wayne S Sossin
    The loss of FMRP does not affect how neuronal ribosomes are stalled or where they are stalled, but reduces the number of neuronal RNA granules that contain stalled ribosomes.
    1. Biochemistry and Chemical Biology
    2. Cell Biology

    DNA tensiometer reveals catch-bond detachment kinetics of kinesin-1, -2, and -3

    Crystal R Noell, Tzu-Chen Ma ... William O Hancock
    All three kinesin transport families exhibit unexpectedly slow dissociation under load, explaining robust competition with dynein during bidirectional cargo transport.
    1. Cancer Biology
    2. Cell Biology

    DuoHexaBody-CD37 induces direct cytotoxic signaling in diffuse large B-cell lymphoma

    Simar Pal Singh, Kumar Mangalam ... Annemiek B van Spriel
    DuoHexaBody‑CD37 triggers complement‑independent cytotoxic signaling in diffuse large B-cell lymphoma (DLBCL), revealing therapeutic pathways that can be exploited to enhance tumor cell killing through targeted combination strategies.
    1. Cell Biology

    Nim1-related kinases regulate septin organization and cytokinesis by modulating Hof1 at the cell division site

    Bindu Bhojappa, Anubhav Dhar ... Saravanan Palani
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Convincing
    1. Cell Biology
    2. Neuroscience

    All-optical analysis of electrical coupling in muscle ensembles reveals contributions of individual innexins to cell synchronization and locomotion

    Nora Elvers, Amelie Bergs ... Alexander Gottschalk
    Not revised
    Reviewed Preprint v1
    • Important
    • Convincing
    1. Cell Biology

    CHOP promotes the transition to chronic integrated stress response signaling with suppression of hepatocyte identity

    Theo F Velarde, Kaihua Liu ... D Thomas Rutkowski
    Not revised
    Reviewed Preprint v1
    • Fundamental
    • Convincing
    1. Cell Biology

    Human mitochondrial DNA variants influence telomere length: evidence from a transmitochondrial cybrid model

    Manon Mahieu, Jean-Philippe Defour ... Anabelle Decottignies
    Not revised
    Reviewed Preprint v1
    • Important
    • Convincing
    1. Cell Biology

    PXGS: a Poly-Transgene Expression System based on Mutually Exclusive Splicing of Dscam

    Renee Yin Yu, Alyeri Bucio-Méndez, Brian E Chen
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
    • Convincing
    1. Cell Biology

    Decoupling AMPK from fatty acid synthesis allows maintenance of fitness late in life

    Hanane Hadj-Moussa, Megan Ulusan ... Jonathan Houseley
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Convincing
    1. Cell Biology

    Cytoplasmic circular dsDNA is a key constituent of stress granules

    Natalia A Demeshkina, Adrian R Ferré-D'Amaré
    Extrachromosomal circular DNA has been identified as a novel component of stress granule cores, indicating its essential involvement in eukaryotic stress response pathways at the level of protein synthesis.
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Highlights

    1. Cell Biology
    2. Neuroscience

    The role of lipids in hearing

    Yein Christina Park, Angela Ballesteros
    1. Cancer Biology
    2. Cell Biology

    Chemotherapy: Lipid balance and chemoresistance in cancer cells

    Kaori Kanemaru, Yoshikazu Nakamura
    1. Biochemistry and Chemical Biology
    2. Cell Biology

    Metabolism: How one nutrient controls cell size

    Angela Montero, Lydia WS Finley

Senior editors

  1. Sofia J Araújo
    University of Barcelona, Spain
  2. Felix Campelo
    Pompeu Fabra University, Spain
  3. Jonathan A Cooper
    Jonathan A Cooper
    Fred Hutchinson Cancer Research Center, United States
  4. See more editors