Cell Biology

Latest articles

1. 1. Cell Biology
   2. Neuroscience

   Engulfment by brain macrophages in a short-lived vertebrate

   Rahul Nagvekar, Angela N Pogson ... Anne Brunet
2. 1. Cell Biology

   Analysis of cancer mutations introduced into the Drosophila melanogaster Notch negative regulatory region uncovers a diversity of regulatory outcomes

   Hideyuki Shimizu, Martin Baron

   Heterogeneity in outcomes of differently located activating mutations of Notch indicates the need and potential for mutant specific targeting of Notch in cancer.
3. 1. Cell Biology
   2. Cancer Biology

   RAB14-dependent tubulovesicular recycling directs MET to invadopodia, promoting TNBC cell invasion

   Amrita Khamari, Atreyee Guria ... Sunando Datta
4. 1. Cell Biology

   Decoupling AMPK from fatty acid synthesis allows maintenance of fitness late in life

   Hanane Hadj-Moussa, Megan Ulusan ... Jonathan Houseley

   Re-engineering a highly conserved metabolic pathway in yeast prevents age-related functional decline and proves that ageing is not inevitably linked to loss of fitness.
5. 1. Cell Biology
   2. Developmental Biology

   Organ Development: Following your heart as it takes shape

   Alexandra Trouilloud, Nicole C Dubois

   A novel computational pipeline reveals patterns of tissue movement and growth in early heart formation and advances virtual modeling of development.
6. 1. Cell Biology
   2. Immunology and Inflammation

   Pink1-mediated mitophagy in the endothelium releases proteins encoded by mitochondrial DNA and activates neutrophil responses during inflammation

   Priyanka Gajwani, Li Wang ... Jalees Rehman

   Inflammatory activation of endothelial cells triggers Pink1-dependent mitophagy and mitochondrial formyl peptides release, which drives neutrophil recruitment and lung injury.
7. 1. Cell Biology
   2. Physics of Living Systems

   The titin N2A-MARP signalosome constrains muscle longitudinal hypertrophy in response to stretch

   Robbert van der Pijl, Jochen Gohlke ... Coen Ottenheijm

   Titin-associated muscle ankyrin repeat proteins limit stretch-induced longitudinal muscle hypertrophy and link titin mechanosensing to mTOR signaling.
8. 1. Cell Biology

   N6-Adenosine Methylation of a Single Site in SARS-CoV-2 5′-UTR Promotes Translation

   Ammar Aly, Gary Scott ... A Pejmun Haghighi
9. 1. Cell Biology
   2. Cancer Biology

   Adaptive plasticity of aspartate metabolism in succinate dehydrogenase-deficient cancer cells

   David Sokolov, Eric Zheng ... Lucas B Sullivan
10. 1. Cell Biology
    2. Neuroscience

    Stable excitatory-inhibitory synapse balance despite dynamic turnover

    Krassimira A Garbett, James P Allen ... Richard C Sando

    Long-term live imaging and tracking approaches reveal a coordination between excitatory and inhibitory synapse assembly, despite continual spatiotemporal dynamics.