Cell Biology

Cell Biology

eLife reviews research spanning vesicle transport and signal transduction to cell cycle and cell polarity and fate. Learn more about what we review and sign up for the latest content.
Illustration by Davide Bonazzi

Latest articles

    1. Cell Biology

    Human dynein–dynactin is a fast processive motor in living cells

    Vikash Verma, Patricia Wadsworth, Thomas J Maresca
    TIRF imaging of CRISPR-edited human cells shows dynein–dynactin complexes move processively with motility parameters consistent with the presence of multi-dynein assemblies (>one dynein heavy chain dimer per dynactin) in cells.
    Version of Record
    Short Report
    • Valuable
    • Convincing
    1. Cancer Biology
    2. Cell Biology

    Uev1A counteracts oncogenic Ras stimuli in both polyploid and diploid cells

    Qi Zhang, Yunfeng Wang ... Shaowei Zhao
    Uev1A and APC/C degrade CycA to counteract oncogenic Ras, thereby protecting against cell death in polyploid Drosophila nurse cells and suppressing overgrowth in diploid germline and human colorectal tumor cells.
    1. Cell Biology

    Engineering ATP Import in Yeast Uncovers a Synthetic Route to Extend Cellular Lifespan

    Naci Oz, Hetian Su ... Alaattin Kaya
    Not revised
    Reviewed Preprint v1
    • Important
    • Incomplete
    1. Cell Biology

    Orderly mitosis shapes interphase genome architecture

    Krishnendu Guin, Adib Keikhosravi ... Tom Misteli
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Solid
    1. Cell Biology

    Specialisation of meiotic kinetochores revealed through a synthetic spindle assembly checkpoint strategy

    Lori B Koch, Tiasha Ghosh ... Adele L Marston
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Convincing
    1. Cell Biology

    THE FAM53C/DYRK1A axis regulates the G1/S transition of the cell cycle

    Taylar Hammond, Jong Bin Choi ... Julien Sage
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Solid
    1. Cell Biology
    2. Genetics and Genomics

    Temporally controlled nervous system-to-gut signaling bidirectionally regulates longevity in C. elegans

    Lingxiu Xu, Chengxuan Han ... Jianfeng Liu
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Convincing
    1. Cell Biology
    2. Medicine

    Uncovering Shared and Tissue-Specific Molecular Adaptations to Intermittent Fasting in Liver, Brain, and Muscle

    Yibo Fan, Senuri De Silva ... Thiruma V Arumugam
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Solid
    1. Cell Biology

    Specific GPCRs elicit unique extracellular vesicle miRNA array signatures

    Xiao Shi, Michelle C Palumbo ... Aaron J Janowsky
    Unique extracellular vesicle microRNA signatures resulting from G protein-coupled receptor activation indicate distinct downstream signaling and functional networks by receptor, with implications for developing new drugs and understanding their long-term and off-target effects.
    1. Cell Biology

    Polo-like kinase phosphorylation of the orphan kinesin KIN-G negatively regulates centrin arm biogenesis in Trypanosoma brucei

    Yasuhiro Kurasawa, Qing Zhou ... Ziyin Li
    Not revised
    Reviewed Preprint v1
    • Important
    • Solid
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Highlights

    1. Structural Biology and Molecular Biophysics
    2. Cell Biology
    3. Biochemistry and Chemical Biology

    Allosteric Regulation of Kinase Activity – call for papers

    1. Cell Biology
    2. Developmental Biology

    Imaging methods are vastly underreported

    Guillermo Marqués, Thomas Pengo, Mark A Sanders
    1. Cell Biology
    2. Developmental Biology

    Philosophy of Biology: Knowledge and illusions

    Antony M Jose

Senior editors

  1. Sofia J Araújo
    University of Barcelona, Spain
  2. Felix Campelo
    Pompeu Fabra University, Spain
  3. Jonathan A Cooper
    Jonathan A Cooper
    Fred Hutchinson Cancer Research Center, United States
  4. See more editors