Cell Biology

Cell Biology

eLife reviews research spanning vesicle transport and signal transduction to cell cycle and cell polarity and fate. Learn more about what we review and sign up for the latest content.
Illustration by Davide Bonazzi

Latest articles

    1. Cell Biology

    The microbiome interacts with the circadian clock and dietary composition to regulate metabolite cycling in the Drosophila gut

    Yueliang Zhang, Sara B Noya ... Amita Sehgal
    The Drosophila microbiome regulates the cycling of gut metabolites in a circadian clock and diet-dependent manner.
    1. Cell Biology

    Quantitative intra-Golgi transport and organization data suggest the stable compartment nature of the Golgi

    Hieng Chiong Tie, Haiyun Wang ... Lei Lu
    Quantitative measurements of intra-Golgi transport kinetics of diverse secretory cargos challenge the classic cisternal progression model and support the stable compartment model of the Golgi.
    1. Cell Biology

    Forward genetics in C. elegans reveals genetic adaptations to polyunsaturated fatty acid deficiency

    Delaney Kaper, Uroš Radović ... Marc Pilon
    Polyunsaturated fatty acids are not genetically replaceable in the nematode C. elegans and only mutations that help free ferrous ions can boost the activity of a poorly functioning desaturase enzyme.
    1. Cell Biology

    Senescence: Returning aging cells to productivity

    Rachana W Vaidya, Simon Y Tang
    Platelet-derived growth factors can restore the proliferative potential of senescent cells taken from the degenerated intervertebral discs of aged humans.
    Version of Record
    Insight
    1. Cell Biology

    The molecular logic of Gtr1/2- and Pib2-dependent TORC1 regulation in budding yeast

    Jacob H Cecil, Cristina M Padilla ... Andrew P Capaldi
    Dual regulation of TORC1 by Gtr1/2 and Pib2 drives cells into three distinct signaling states, establishing a new paradigm for graded TORC1 signaling.
    1. Cell Biology
    2. Medicine

    The ESCRT protein CHMP5 restricts bone formation by controlling endolysosome-mitochondrion-mediated cell senescence

    Fan Zhang, Yuan Wang ... Xianpeng Ge
    CHMP5 is crucial in preventing skeletal progenitor cell senescence and abnormal bone formation, and senolytic drugs represent potential therapeutic medicine for musculoskeletal abnormalities associated with a dysfunctional endolysosomal pathway.
    1. Cell Biology
    2. Neuroscience

    Endophilin A1 facilitates organization of the GABAergic postsynaptic machinery to maintain excitation-inhibition balance

    Xue Chen, Deng Pan ... Yanrui Yang
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Solid
    1. Cell Biology

    Negative regulation of miRNA sorting into EVs is mediated by the capacity of RBP PCBP2 to impair the SYNCRIP-dependent miRNA loading

    Francesco Marocco, Sabrina Garbo ... Marco Tripodi
    PCBP2 promotes miRNA cell retention by counteracting SYNCRIP-dependent miRNAs EV loading.

Senior editors

  1. Felix Campelo
    Pompeu Fabra University, Spain
  2. Jonathan A Cooper
    Jonathan A Cooper
    Fred Hutchinson Cancer Research Center, United States
  3. Richard M White
    Ludwig Institute for Cancer Research, University of Oxford, United Kingdom
  4. See more editors