Cell Biology

Latest articles

1. 1. Cell Biology

   Secreted exosomes induce filopodia formation

   Caitlin McAtee, Mikin R Patel ... Alissa M Weaver

   Exosome-associated THSD7A is identified as a key trigger of filopodia formation in cancer cells and neurons, revealing a novel pathway with implications for metastasis, neuronal connectivity, and other filopodia-dependent processes.
2. 1. Cell Biology

   MIRO1 controls energy production and proliferation of vascular smooth muscle cells

   Lan Qian, Olha M Koval ... Isabella M Grumbach
3. 1. Cancer Biology
   2. Cell Biology

   Chemotherapy: Lipid balance and chemoresistance in cancer cells

   Kaori Kanemaru, Yoshikazu Nakamura

   A shift in the balance between two lipids – cholesterol and sphingomyelin – makes hybrid epithelial-mesenchymal cancer cells less responsive to certain chemotherapy drugs.
4. 1. Cell Biology

   Overexpression of Ssd1 and calorie restriction extend yeast replicative lifespan by preventing deleterious age-dependent iron uptake

   J Ignacio Gutierrez, Claudia Edgar, Jessica K Tyler

   Live imaging analyses in budding yeast reveal that calorie restriction and overexpression of the mRNA binding protein Ssd1 both block deleterious age-dependent iron uptake as a mechanism to extend lifespan.
5. 1. Cell Biology
   2. Neuroscience

   Dilated cardiomyopathy-associated RNA-binding motif protein 20 regulates long pre-mRNAs in neurons

   Giulia Di Bartolomei, Raúl Ortiz ... Peter Scheiffele

   An alternative splicing regulator previously implicated in calcium signaling in the heart ensures cell-type-specific mRNA processing of long neuronal mRNAs in the mouse brain.
6. 1. Cell Biology

   Chemotherapy resistance due to epithelial-to-mesenchymal transition is caused by abnormal lipid metabolic balance

   Atsushi Matsumoto, Akihito Inoko ... Junichi Ikenouchi

   Lipid imbalance triggered by Snail-driven epithelial–mesenchymal transition creates a cholesterol-dependent vulnerability that can be therapeutically targeted to overcome chemoresistance in cancer.
7. 1. Cell Biology
   2. Genetics and Genomics

   Cross-species evaluation of TANGO2 homologs, including HRG-9 and HRG-10 in Caenorhabditis elegans, challenges a proposed role in heme trafficking

   Sarah E Sandkuhler, Kayla S Youngs ... Samuel J Mackenzie

   Evidence from multiple model systems supports a shift away from heme transport and toward metabolic dysfunction and oxidative stress as key drivers of TANGO2 deficiency.
8. 1. Cell Biology

   Centrosome Migration and Apical Membrane Formation in Polarized Epithelial Cells: Insights from the MDCK Cyst Model

   Po-Kai Wang, Keng-Hui Lin, Tang K Tang
9. 1. Cell Biology
   2. Microbiology and Infectious Disease

   Decoding the biogenesis of HIV-induced CPSF6 puncta and their fusion with nuclear speckles

   Chiara Tomasini, Celine Cuche ... Francesca Di Nunzio

   HIV hijacks SRRM2 to enlarge nuclear speckles, stabilizing CPSF6 puncta and promoting efficient viral replication.
10. 1. Cell Biology

    A conserved Hsp70 phosphorylation regulates cell cycle progression after DNA damage

    Thomas Moss, Alexandra Wooldredge ... Shaeri Mukherjee