Cell Biology

Latest articles

1. 1. Cell Biology

   An ancient transcription factor functions as the master regulator of primary cilia formation

   Weihua Wang, Xiqi Zhang ... Zhangfeng Hu
2. 1. Cell Biology
   2. Computational and Systems Biology

   Geometry shapes cytoplasmic Cdk1 waves that drive cortical dynamics

   Daniel Cebrián-Lacasa, Marcin Leda ... Lendert Gelens
3. 1. Cancer Biology
   2. Cell Biology

   Mitochondrial ETF insufficiency drives neoplastic growth by selectively optimizing cancer bioenergetics

   David Papadopoli, Ranveer Palia ... Ivan Topisirovic

   Downregulation of the electron transfer flavoprotein dehydrogenase drives pro-tumorigenic metabolic programs via stimulating the mechanistic Target of Rapamycin Complex 1 signaling across a broad spectrum of cancers.
4. 1. Cell Biology
   2. Structural Biology and Molecular Biophysics

   Unbend, correction of local beam-induced sample motion in cryo-EM images using a 3D spline model

   Lingli Kong, Ximena Zottig ... Nikolaus Grigorieff

   Movie alignment software uses a 3D spline model to capture beam-induced motion in cryo-electron microscopy movie frames, correct local sample distortions, and improve two-dimensional template matching signal-to-noise ratios in the corrected images.
5. 1. Cell Biology

   The FAM53C/DYRK1A axis regulates the G1/S transition of the cell cycle

   Taylar Hammond, Jong Bin Choi ... Julien Sage

   The poorly characterized FAM53C protein is an inhibitor of the DYRK1A kinase and governs the G1/S transition of the cell cycle.
6. 1. Cell Biology
   2. Developmental Biology

   Prickle and Ror modulate Dishevelled-Vangl interaction to regulate non-canonical Wnt signaling during convergent extension in Xenopus

   Hwa-seon Seo, Deli Yu ... Jianbo Wang

   During convergent extension morphogenesis, non-canonical Wnt induces the signal transducer Dishevelled to transition from Vangl to Frizzled, a process that is inhibited by Prickle but facilitated by the co-receptor Ror.
7. 1. Cell Biology

   Single-cell lineage tracing identifies hemogenic endothelial cells in the adult mouse bone marrow

   Jing-Xin Feng, Mei-Ting Yang ... Giovanna Tosato

   Single-cell and bulk lineage tracing reveals that adult bone marrow endothelial cells generate functional hematopoietic progenitor and mature blood cells, expanding the cell sources of postnatal hematopoiesis.
8. 1. Cell Biology

   Ubiquitin Ligase ITCH Regulates Life Cycle of SARS-CoV-2 Virus

   Qiwang Xiang, Camille Wouters ... Jiou Wang
9. 1. Cell Biology
   2. Immunology and Inflammation

   Clathrin-independent endocytosis and retrograde transport in cancer cells tune immune synapse organization and CD8 T cell response

   Shiqiang Xu, Alix Buridant ... Henri-François Renard

   Endophilin-A3-mediated clathrin-independent endocytosis and retrograde trafficking in cancer cells regulate ICAM1 organization at the immune synapse and influence cytotoxic CD8 T cell response.
10. 1. Cell Biology
    2. Developmental Biology

    Zinc is a Key Regulator of the Sperm-Specific K⁺ Channel (Slo3) Function

    Rizki Tsari Andriani, Tanadet Pipatpolkai ... Takafumi Kawai