Research Articles published by eLife are full-length studies that present important breakthroughs across the life sciences and biomedicine. There is no maximum length and no limits on the number of display items.
Adriana Quijada-Freire, César A Santiago ... Mario Mellado
HIV-1 remodels the spatial organization of its co-receptor, CXCR4, on T cell membranes, showing that viral entry requires receptor clustering rather than simple receptor binding.
Ryan T Maloney, Athena Q Ye ... Benjamin L de Bivort
Individual flies have idiosyncratic preferences that shift over their lifetime in a way that depends on genotype and may be adaptive to rapidly changing environmental pressures.
In a stylized regime-shift detection task, human fMRI evidence shows that under- and overreactions to change arise from dissociable contributions of the frontoparietal network and ventromedial prefrontal cortex.
Marion Brickwedde, Rupali Limachya ... Ali Mazaheri
Early visual alpha oscillations correlate on a trial-by-trial basis with steady-state responses at later stages of the processing stream, implying a role in signal enhancement and interareal communication.
Francisco Muñoz-Carvajal, Nicole Sanhueza ... Felipe A Court
Age-related epigenetic regulation of mitochondrial stress responses drives neuronal degeneration and sensory decline, highlighting mitochondrial resilience as a potential target to preserve brain function during aging.
Modeling approaches demonstrate utility for incidence and reproductive number prediction and have potential to complement traditional surveillance in real time to guide public health interventions.
Humans’ flexible temporal cognition, including mental time travel, arises from perspective-agnostic encoding of event sequences in the hippocampus and perspective-dependent retrieval and reconstruction in the posterior parietal cortex.
