Research Articles published by eLife are full-length studies that present important breakthroughs across the life sciences and biomedicine. There is no maximum length and no limits on the number of display items.
Maryam Karimian, Mark Jonathan Roberts ... Mario Senden
Principles of weakly coupled oscillators capture human figure-ground segregation and its training-induced enhancement, indicating gamma synchrony remains a plausible grouping mechanism.
Genetic and biochemical analyses show that loss of the E3 ubiquitin ligases ZNRF3 and RNF43 enhances EGFR signaling by impairing EGFR ubiquitination and degradation, revealing a new cancer-promoting mechanism.
The ability to predict brain activity from words before they occur can be explained by information shared between neighbouring words, without requiring next-word prediction by the brain.
Farjana Islam, Cayman Williams ... Benedict Seddon
Inhibitor of κB kinase signalling differentially controls development and survival of γδ T cell subsets through nuclear factor-κB activation and repression of receptor-interacting protein kinase 1-driven necroptosis, revealing distinct inflammatory signalling requirements from αβ T cells.
Detecting replay during longer time periods (e.g. resting state or sleep) with temporally delayed linear modeling (TDLM) requires biologically implausible event densities, and purely synthetic simulations substantially overestimate the method's sensitivity.
The phase of cortical activity, measured in the gray matter, is organized at multiple spatial scales, with the largest scales explaining most variance in phase at a given temporal frequency.
A system to enrich yeast in metaphase of mitosis, meiosis I, or meiosis II reveals reduced spindle assembly checkpoint robustness in meiosis I and distinct kinetochore composition and phosphorylation states.
Elucidation of the Hox code defining forelimb positioning provides novel insights into lateral plate mesoderm patterning and the integration of vertebrate column structure and limb positioning.
