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  1. Plain-language Summaries of Research: Something for everyone

    Sarah Shailes
    Journals and other scientific organizations produce a diverse variety of plain-language summaries.
    1. Cancer Biology
    2. Cell Biology

    Genetic Diversity: Driving cancer evolution

    Devon M Fitzgerald, Susan M Rosenberg
    Tumor-growth-factor-beta signaling helps cancer cells to evolve and become resistant to drugs by down-regulating accurate DNA repair.
    Version of Record
    Insight
    1. Structural Biology and Molecular Biophysics

    Ion Channels: From ions to insulin

    Voula Kanelis
    Electron cryo-microscopy has revealed the three-dimensional structure of a potassium channel that has a central role in regulating the release of insulin from the pancreas.
    Version of Record
    Insight
    1. Cell Biology

    Cell Division: How centrioles acquire the ability to reproduce

    Midori Ohta, Arshad Desai, Karen Oegema
    A protein called SAS-7 is required for daughter centrioles to become mothers in C. elegans.
    Version of Record
    Insight
    1. Biochemistry and Chemical Biology
    2. Cell Biology

    TOR Signaling: A central role for a region in the middle

    Edward Stuttfeld, Stefan Imseng, Timm Maier
    A domain called the 'Conserved region in the middle' is responsible for target recognition in the TORC2 complex in fission yeast and the mTORC2 complex in mammals.
    Version of Record
    Insight
    1. Chromosomes and Gene Expression

    Paternal Effects: Like father, like son

    Claude Becker
    Exposing male mice to nicotine or cocaine enables their male offspring to cope with high doses of either, which suggests that such paternal effects are generic, rather than being a response to a specific type of stress.
    Version of Record
    Insight
    1. Ecology
    2. Evolutionary Biology

    Point of View: Towards a mechanistic foundation of evolutionary theory

    Michael Doebeli, Yaroslav Ispolatov, Burt Simon
    A description of evolution that is based on birth-death processes, and in which fitness is at most a derived quantity, is advocated.
  2. February 2017

    Episode 36: February 2017

    In this episode we hear about epilepsy, the sushi-belt model of transport in neurons, a mother in ancient Troy, the Amazon rainforest and bias in scientific reporting.
    1. Biochemistry and Chemical Biology
    2. Cell Biology

    Cell Cycle: Micromanaging checkpoint proteins

    Andrea Ciliberto, Silke Hauf
    The kinase Mps1, long known to be the 'boss' in mitotic checkpoint signaling, phosphorylates multiple proteins in the checkpoint signaling cascade.
    Version of Record
    Insight
  3. Core strengths: an interview with Diana Ordonez

    Of all the tools that Diana Ordonez used to study populations of immune cells during her PhD and postdoc research, flow cytometry was the most important. Now she uses her experience and skills to advise and support other researchers as a Flow Cytometrist at the European Molecular Biology Laboratory (EMBL) in Heidelberg, Germany.