Magazine

Highlighting the latest research and giving a voice to scientists
Illustration by Davide Bonazzi

Highlights

    1. Neuroscience

    Cilia reveal their secrets

    Ruth Anne Eatock, Marina Kabirova
    1. Neuroscience

    The sound of neural silence

    Nikki Tjahjono, Yu-Shun Wang, Lin Tian
    1. Neuroscience

    Testing 'next-word prediction'

    Richard J Antonello
    1. Evolutionary Biology
    2. Immunology and Inflammation

    Language models for antibodies

    Antonio Matas-Gil, Andreas Tiffeau-Mayer

Highlights controls:

Latest articles

    1. Biochemistry and Chemical Biology

    Lipid Transport: How membranes shape up for lipid transfer

    Takashi Hirashima, Toshiya Endo
    The extraction of a phospholipid called phosphatidic acid from the mitochondrial outer membrane is regulated by the curvature of this membrane.
    Version of Record
    Insight
    1. Neuroscience

    Vestibular Hair Cells: Are kinocilia motile?

    Ruth Anne Eatock, Marina Kabirova
    Gene expression patterns in the inner ear put an old question about structures called kinocilia back in motion.
    Version of Record
    Insight
    1. Neuroscience

    Neurotransmitters: The sound of neural silence

    Nikki Tjahjono, Yu-Shun Wang, Lin Tian
    A new fluorescent sensor makes it possible to track the neurotransmitter GABA in freely moving animals.
    Version of Record
    Insight
    1. Neuroscience

    Language Models: Does the brain really know what word is coming next?

    Richard J Antonello
    Apparent neural encoding of future words may arise from the statistical structure of language itself, rather than from predictive computations in the brain.
    Version of Record
    Insight
    1. Genetics and Genomics
    2. Medicine

    Point of View: Teaching early-career researchers how to respond to peer reviewers

    Eric Kalkhoven, Manon Kluijtmans
    Responding to reports from peer reviewers is a crucial part of scientific publishing, but early-career researchers are rarely taught about this process.
    1. Evolutionary Biology
    2. Immunology and Inflammation

    Antibody Language Models: Taking the biology seriously makes models better

    Antonio Matas-Gil, Andreas Tiffeau-Mayer
    A new biologically-informed training paradigm enables protein language models to predict affinity maturation trajectories for antibodies.
    Version of Record
    Insight
    1. Neuroscience

    Neuroanatomy: Hidden folds reveal brain organization

    Jürgen Germann
    Previously underappreciated folds in the cerebral cortex provide insight into how its structure varies across individuals.
    Version of Record
    Insight
    1. Neuroscience

    Orbitofrontal Cortex: Cocaine disrupts hidden states in the brain

    Margo Le, Ronald Keiflin
    Cocaine use disrupts the encoding of abstract states in the orbitofrontal cortex.
    Version of Record
    Insight
    1. Structural Biology and Molecular Biophysics

    Glycobiology: How enzymes make the right choice during biosynthesis

    Ana S Ramírez, Camilo Perez
    The biosynthesis of an important biopolymer called hyaluronan requires an enzyme that discriminates between two different substrates.
    Version of Record
    Insight
    1. Neuroscience

    Memory Encoding and Retrieval: Rethinking how memories are retrieved

    Rocco Pizzarelli, Marilena Griguoli
    Patterns of neural activity called theta oscillations have a role in memory encoding but – contrary to current thinking – do not appear to have a role in memory retrieval.
    Version of Record
    Insight