5,040 results found
    1. Biochemistry and Chemical Biology

    Dysfunctional TRPM8 signalling in the vascular response to environmental cold in ageing

    Dibesh Thapa, Joäo de Sousa Valente ... Susan D Brain
    Cold detecting thermoreceptor TRPM8's signalling is diminished with ageing which leads to an impaired response to cold observed in ageing.
    1. Chromosomes and Gene Expression

    A genetic program mediates cold-warming response and promotes stress-induced phenoptosis in C. elegans

    Wei Jiang, Yuehua Wei ... Dengke K Ma
    A gene regulatory program regulating thermal stress response and organismic death.
    1. Microbiology and Infectious Disease

    Host genetic selection for cold tolerance shapes microbiome composition and modulates its response to temperature

    Fotini Kokou, Goor Sasson ... Itzhak Mizrahi
    Microbiome and transcriptomic profiling of genetically selected tropical fish with high and low tolerance to cold exposure revealed host control over microbiome composition and response to temperature changes.
    1. Computational and Systems Biology
    2. Genetics and Genomics

    Comparative multi-tissue profiling reveals extensive tissue-specificity in transcriptome reprogramming during thermal adaptation

    Noushin Hadadi, Martina Spiljar ... Mirko Trajkovski
    Integrative analysis of multi-tissue transcriptomics data of mice subjected to cold, mild warm or room temperature places the thermal adaptation of individual tissues in a whole-organism perspective.
    1. Biochemistry and Chemical Biology

    AMPK signaling to acetyl-CoA carboxylase is required for fasting- and cold-induced appetite but not thermogenesis

    Sandra Galic, Kim Loh ... Bruce E Kemp
    A single mutation in acetyl-CoA carboxylase blocking AMPK regulation inhibits food intake in mice in response to cold exposure or fasting causing them to lose weight.
    1. Ecology
    2. Plant Biology

    Locally adaptive temperature response of vegetative growth in Arabidopsis thaliana

    Pieter Clauw, Envel Kerdaffrec ... Magnus Nordborg
    Growth of Arabidopsis seedlings at low temperatures differs between plants that hail from different parts of the world in a way that suggests climate adaptation.
    1. Neuroscience

    Cold-induced hyperphagia requires AgRP neuron activation in mice

    Jennifer D Deem, Chelsea L Faber ... Gregory J Morton
    A combination of neuroscience approaches and indirect calorimetry demonstrate a physiological role for AgRP neurons in cold-induced hyperphagia and strongly suggest temperature is an important regulator of AgRP neuron activity.
    1. Evolutionary Biology

    Evolutionary footprints of a cold relic in a rapidly warming world

    Eva Wolf, Emmanuel Gaquerel ... Marcus A Koch
    Evolutionary dynamics of polyploid plants of the genus Cochlearia during past periods of rapid climate change indicate increased rates of speciation and diversification in response to pronounced glacial cycles and cold periods in particular.
    1. Neuroscience

    Keratinocytes contribute to normal cold and heat sensation

    Katelyn E Sadler, Francie Moehring, Cheryl L Stucky
    Purinergic keratinocyte-to-sensory neuron signaling is a ubiquitous amplification mechanism that is required for normal mechanical, cold, and heat sensation in vivo.
    1. Ecology
    2. Plant Biology

    Seasonal shift in timing of vernalization as an adaptation to extreme winter

    Susan Duncan, Svante Holm ... Caroline Dean
    An adaptation to extreme winter has involved a shift to autumn temperature monitoring.

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