300 results found
    1. Medicine
    2. Neuroscience

    Digital wearable insole-based identification of knee arthropathies and gait signatures using machine learning

    Matthew F Wipperman, Allen Z Lin ... Olivier Harari
    Biosensor data collected by digital insoles is comparable to lab-based clinical assessments and can be used to identify subject-specific gait patterns.
    1. Evolutionary Biology
    2. Medicine

    APOE4 is associated with elevated blood lipids and lower levels of innate immune biomarkers in a tropical Amerindian subsistence population

    Angela R Garcia, Caleb Finch ... Benjamin C Trumble
    The relationship between APOE genotype and disease risks may be environmentally moderated, with APOE4 being less harmful and unlikely to increase cardiometabolic risk in a physically active, energy-limited population.
    1. Cancer Biology
    2. Immunology and Inflammation

    Topography of cancer-associated immune cells in human solid tumors

    Jakob Nikolas Kather, Meggy Suarez-Carmona ... Niels Halama
    Spatial patterns of lymphoid and myeloid cells in human solid tumors differ between cancer types, yielding a new classification of anti-tumor host response.
    1. Epidemiology and Global Health

    Quantification of the pace of biological aging in humans through a blood test, the DunedinPoAm DNA methylation algorithm

    Daniel W Belsky, Avshalom Caspi ... Terrie E Moffitt
    Methylation pace of aging is a novel measure requiring only a blood sample that clinical-trial and observational studies can use to test if treatments modify how fast participants are aging.
    1. Medicine
    2. Computational and Systems Biology

    Calibration and validation strategy for electromechanical cardiac digital twins

    Zhinuo Jenny Wang, Maxx Holmes ... Blanca Rodriguez
    Not revised
    Reviewed Preprint v1
    • Important
    • Solid
    • Incomplete
    1. Developmental Biology
    2. Stem Cells and Regenerative Medicine

    Cell-free DNA as a potential biomarker of differentiation and toxicity in cardiac organoids

    Brian Silver, Kevin Gerrish, Erik Tokar
    Cardiac organoids have potential as a tool used for identifying cell-free DNA as biomarkers for toxicity and severity of exposure outcomes.
    1. Medicine
    2. Neuroscience

    Plasma extracellular vesicle synaptic proteins as biomarkers of clinical progression in patients with Parkinson’s disease

    Chien-Tai Hong, Chen-Chih Chung ... Lung Chan
    The promising potential of plasma extracellular vesicle synaptic proteins as clinical biomarkers of disease progression in Parkinson's disease has been presented.
    1. Neuroscience

    Hippocampome.org: a knowledge base of neuron types in the rodent hippocampus

    Diek W Wheeler, Charise M White ... Giorgio A Ascoli
    Hippocampome.org is an online resource that provides free human- and machine-readable access to the comprehensive property-based classification of hippocampal neurons from 14,000 pieces of published experimental evidence.
    1. Cell Biology

    Mitochondrial flashes regulate ATP homeostasis in the heart

    Xianhua Wang, Xing Zhang ... Heping Cheng
    Mitochondrial flashes counteract the imbalance of ATP supply-and-demand and constitute an auto-regulator of ATP homeostasis in the heart.
    1. Neuroscience

    Combining magnetoencephalography with magnetic resonance imaging enhances learning of surrogate-biomarkers

    Denis A Engemann, Oleh Kozynets ... Alexandre Gramfort
    Predicting age jointly from multimodal brain images and electrophysiology with machine learning enhances detecting health issues and facets of cognitive decline.

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