15 results found
    1. Developmental Biology
    2. Genetics and Genomics

    Nuclear receptor Ftz-f1 promotes follicle maturation and ovulation partly via bHLH/PAS transcription factor Sim

    Elizabeth M Knapp, Wei Li ... Jianjun Sun
    Genetic analyses illustrate the novel requirement of Ftz-f1 and Sim in adult Drosophila ovaries for regulating follicle cell differentiation and ovulation that is likely conserved in mammals.
    1. Developmental Biology

    Spatiotemporally controlled genetic perturbation for efficient large-scale studies of cell non-autonomous effects

    Andrea Chai, Ana M Mateus ... Rita Sousa-Nunes
    A novel genetic strategy for induction of reproducible neural tumors (or any other deleterious phenotype) in a single Drosophila stock (applicable to other organisms).
    1. Computational and Systems Biology
    2. Developmental Biology

    Odd-paired controls frequency doubling in Drosophila segmentation by altering the pair-rule gene regulatory network

    Erik Clark, Michael Akam
    The organisation of the Drosophila embryo into segmental units is orchestrated by combinatorial regulatory interactions between spatially patterned and temporally patterned transcription factors.
    1. Chromosomes and Gene Expression
    2. Microbiology and Infectious Disease

    A transcriptomic atlas of Aedes aegypti reveals detailed functional organization of major body parts and gut regional specializations in sugar-fed and blood-fed adult females

    Bretta Hixson, Xiao-Li Bing ... Nicolas Buchon
    RNAseq profiles of female Aedes body parts, gut regions, and blood-fed guts provide insight into the anatomical patterning of immune and digestive function, and demonstrate the sequential induction of multiple peptidase cohorts over the course of blood meal digestion.
    1. Developmental Biology
    2. Stem Cells and Regenerative Medicine

    Damage-responsive, maturity-silenced enhancers regulate multiple genes that direct regeneration in Drosophila

    Robin E Harris, Michael J Stinchfield ... Iswar K Hariharan
    The reduced ability of Drosophila imaginal discs to regenerate as they mature can be explained by the silencing of damage-responsive enhancers that regulate expression of genes required for regeneration.
    1. Physics of Living Systems

    Geometric control of myosin II orientation during axis elongation

    Matthew F Lefebvre, Nikolas H Claussen ... Sebastian J Streichan
    During Drosophila axis elongation, the orientational pattern of the cytoskeleton is in good approximation stationary, while the genes thought to instruct these patterns are transported with the tissue flow.
    1. Genetics and Genomics

    Converting endogenous genes of the malaria mosquito into simple non-autonomous gene drives for population replacement

    Astrid Hoermann, Sofia Tapanelli ... Nikolai Windbichler
    Minimal genetic modifications of endogenous mosquito genes allow the tissue-specific expression of anti-malarial effectors and convert them into efficient non-autonomous gene drives.
    1. Chromosomes and Gene Expression
    2. Developmental Biology

    Zygotic pioneer factor activity of Odd-paired/Zic is necessary for late function of the Drosophila segmentation network

    Isabella V Soluri, Lauren M Zumerling ... Shelby A Blythe
    Mechanisms for shaping the chromatin accessibility landscape operate during development to regulate how embryonic patterning information is interpreted at the level of gene regulatory networks.
    1. Neuroscience
    2. Genetics and Genomics

    Ecdysone acts through cortex glia to regulate sleep in Drosophila

    Yongjun Li, Paula Haynes ... Amita Sehgal
    Effects of ecdysone on sleep are mediated through lipid metabolism in cortex glia.
    1. Cancer Biology
    2. Computational and Systems Biology

    Single-cell transcriptomics identifies Keap1-Nrf2 regulated collective invasion in a Drosophila tumor model

    Deeptiman Chatterjee, Caique Almeida Machado Costa ... Wu-Min Deng
    Comprehensive transcriptomic analyses describe the underlying tumorigenic gene expression state in the invasive Drosophila follicle cells following the loss of epithelial cell polarity and identify a non-canonical role of Keap1-Nrf2 signaling in regulating collective cell invasion.

Refine your results by:

Type
Research categories