Browse our latest Cell Biology articles

Quantitative measurements of intra-Golgi transport kinetics of diverse secretory cargos challenge the classic cisternal progression model and support the stable compartment model of the Golgi.

Dual regulation of TORC1 by Gtr1/2 and Pib2 drives cells into three distinct signaling states, establishing a new paradigm for graded TORC1 signaling.

CHMP5 is crucial in preventing skeletal progenitor cell senescence and abnormal bone formation, and senolytic drugs represent potential therapeutic medicine for musculoskeletal abnormalities associated with a dysfunctional endolysosomal pathway.

PCBP2 promotes miRNA cell retention by counteracting SYNCRIP-dependent miRNAs EV loading.

The jellyfish embryonic body axis is globally coordinated by conserved planar cell polarity (PCP) mechanisms and oriented by localised Wnt3 in two steps, highlighting PCP’s role in animal axis evolution.

Focal adhesion derived p130Cas condensates regulate translation in an adhesion strength dependent manner.

MYL3 is identified as a novel receptor enabling nervous necrosis virus (NNV) entry via macropinocytosis, revealing a therapeutic target for combating NNV outbreaks in aquaculture.

AlphaFold-guided in vitro and in vivo analyses establish the mechanism of ULK complex formation and provide a structural basis for understanding its role in mammalian autophagy initiation.

Self-supervised deep learning models can accurately perform 3D segmentation of cell nuclei in complex biological tissues, enabling scalable analysis in settings with limited or no ground truth annotations.