Nathaniel Paul Meyer, Tania Singh ... Diane L Barber
Clonal naïve human embryonic stem cells assemble an Arp2/3 complex-dependent contractile actin filament ring around colonies that promotes tensional forces favoring cell-cell adhesion and nuclear translocation of YAP to maintain ground-state pluripotency.
Modulation of division plane rotation in proliferating chondrocytes determines the ratio of clusters and columns, which may support the multifunctional design of the growth plate.
Seiichi Koike, Masashi Tachikawa ... Masayuki Masu
There are two distinct modes of late endosome fusion in the mouse yolk sac visceral endoderm cells and actin dynamics plays a role in regulating vesicle fusion.
DYRK1A, a kinase associated with intellectual developmental disorders and organ growth regulation, functions in cell growth by promoting mTORC1 activity.