Browse our latest Cell Biology articles

Page 187 of 327
    1. Cell Biology
    2. Developmental Biology

    Matrix metalloproteinase 1 modulates invasive behavior of tracheal branches during entry into Drosophila flight muscles

    Julia Sauerwald, Wilko Backer ... Stefan Luschnig
    Tracheal-derived matrix metalloproteinase 1 activity sustains tracheal branch invasion into myotubes by modulating ECM properties and dynamic behavior of sprouting tip cells.
    1. Cell Biology

    Regulated spindle orientation buffers tissue growth in the epidermis

    Angel Morrow, Julie Underwood ... Terry Lechler
    The epidermis uses regulated spindle orientation to maintain robust homeostasis in response to perturbations in proliferation or differentiation.
    1. Cell Biology
    2. Neuroscience

    Implementation of an antibody characterization procedure and application to the major ALS/FTD disease gene C9ORF72

    Carl Laflamme, Paul M McKeever ... Peter S McPherson
    An easy-to-implement antibody validation pipeline addresses the reproducibility crisis resulting from the use of non-specific antibodies.
    1. Cell Biology
    2. Genetics and Genomics

    The Mars1 kinase confers photoprotection through signaling in the chloroplast unfolded protein response

    Karina Perlaza, Hannah Toutkoushian ... Silvia Ramundo
    A genetic screen in a unicellular photosynthetic organism uncovers the first essential signaling component in the chloroplast unfolded protein response that relays information from the chloroplast to the nuclear compartment.
    1. Cell Biology
    2. Genetics and Genomics

    Protein Homeostasis: How chloroplasts protect themselves from unfolded proteins

    Felix Kessler, Paolo Longoni
    A genetic screen has identified the first signaling component of the unfolded protein response in chloroplasts.
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    1. Cell Biology
    2. Evolutionary Biology

    The regulation of oocyte maturation and ovulation in the closest sister group of vertebrates

    Shin Matsubara, Akira Shiraishi ... Honoo Satake
    Oocyte maturation and ovulation in the sister group of vertebrates, Ciona intestinalis Type A, are triggered by Ci-VP, the Ciona homolog of a typical neruopeptide, vasopressin.
    1. Cell Biology
    2. Developmental Biology

    BMP7 functions predominantly as a heterodimer with BMP2 or BMP4 during mammalian embryogenesis

    Hyung-Seok Kim, Judith Neugebauer ... Jan L Christian
    Endogenous BMP2/7 and BMP4/7 heterodimers form in vivo, and are the predominant functional ligand in many, if not all, tissues of developing mouse embryos.
    1. Cell Biology

    Cytoplasmic protein misfolding titrates Hsp70 to activate nuclear Hsf1

    Anna E Masser, Wenjing Kang ... Claes Andréasson
    Hsp70 restricts DNA binding activity of Hsf1 to control the width and amplitude of the heat-shock regulon.
    1. Cell Biology

    Stimulation of Piezo1 by mechanical signals promotes bone anabolism

    Xuehua Li, Li Han ... Jinhu Xiong
    Mechanical stimuli activate Piezo1 in osteoblast lineage cells and thereby promote bone formation in part via Wnt1.
    1. Cell Biology

    Bone Formation: Sensing the load

    Nele Haelterman, Joohyun Lim
    How does the skeleton detect and adapt to changes in the mechanical load it has to carry?
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    Insight