Chromosomes and Gene Expression

Latest articles

1. 1. Chromosomes and Gene Expression
   2. Medicine

   LncRNA-Snhg3 Aggravates Hepatic Steatosis by Regulating PPARγ via SND1/H3K27me3

   Xianghong Xie, Mingyue Gao ... Xiaojun Liu
2. 1. Chromosomes and Gene Expression
   2. Immunology and Inflammation

   Dynamic chromatin architecture identifies new autoimmune-associated enhancers for IL2 and novel genes regulating CD4+ T cell activation

   Matthew C. Pahl, Prabhat Sharma ... Andrew D. Wells
3. 1. Chromosomes and Gene Expression
   2. Developmental Biology

   Dynamic modes of Notch transcription hubs conferring memory and stochastic activation revealed by live imaging the co-activator Mastermind

   F Javier DeHaro-Arbona, Charalambos Roussos ... Sarah Bray

   Live imaging of the Notch co-activator Mastermind reveals that it promotes the formation of a dynamic transcription hub in Notch ON nuclei, conferring probabilistic transcription and providing a template for signal memory.
4. 1. Chromosomes and Gene Expression

   Connecting Chromatin Structures to Gene Regulation Using Dynamic Polymer Simulations

   Yi Fu, Finnegan Clark ... Timothee Lionnet
5. 1. Chromosomes and Gene Expression

   Comparative transcriptomics reveal a novel tardigrade specific DNA binding protein induced in response to ionizing radiation

   M. Anoud, E. Delagoutte ... J-P. Concordet
6. 1. Chromosomes and Gene Expression

   The role of RNA in the maintenance of chromatin domains as revealed by antibody mediated proximity labelling coupled to mass spectrometry

   Rupam Choudhury, Anuroop Venkateswaran Venkatasubramani ... Axel Imhof
7. 1. Chromosomes and Gene Expression

   Transcription Factor Condensates Mediate Clustering of MET Regulon and Enhancement in Gene Expression

   James Lee, Leman Simpson ... Lu Bai
8. 1. Cancer Biology
   2. Chromosomes and Gene Expression

   Ribosome subunit attrition and activation of the p53–MDM4 axis dominate the response of MLL-rearranged cancer cells to WDR5 WIN site inhibition

   Gregory Caleb Howard, Jing Wang ... William P Tansey

   Analysis of the action of WDR5 inhibitors in leukemia cells reveals decreased ribosome inventory, impaired protein synthesis, induction of nucleolar stress, and activation of p53 via alternative splicing of MDM4.
9. 1. Chromosomes and Gene Expression
   2. Evolutionary Biology

   The domesticated transposon protein L1TD1 associates with its ancestor L1 ORF1p to promote LINE-1 retrotransposition

   Gülnihal Kavaklıoğlu, Alexandra Podhornik ... Christian Seiser
10. 1. Chromosomes and Gene Expression
    2. Immunology and Inflammation

    Foxp3 depends on Ikaros for control of regulatory T cell gene expression and function

    Rajan M Thomas, Matthew C Pahl ... Andrew D Wells

    Foxp3 and Ikaros, two transcription factors genetically linked to autoimmune disease in humans, cooperate to establish the epigenomic and transcriptomic landscape of regulatory T cells.