Chromosomes and Gene Expression

Chromosomes and Gene Expression

eLife reviews research ranging from transcription and RNA processing to epigenetics and chromatin biology. Learn more about what we review and sign up for the latest research.
Illustration by Davide Bonazzi

Latest articles

    1. Chromosomes and Gene Expression
    2. Plant Biology

    Short heat shock factor A2 regulates heat resistance and growth balance in Arabidopsis

    Wanxia Chen, Jiaqi Zhao ... Xiaoting Qi
    Short heat shock factor variants prevent hyperactivation of thermotolerance through a noncanonical heat shock response, thereby balancing heat stress response and plant growth.
    1. Chromosomes and Gene Expression

    Identification of the Regulatory Elements and Protein Substrates of Lysine Acetoacetylation

    Qianyun Fu, Terry Nguyen ... Y George Zheng
    Revised
    Reviewed Preprint v2
    Updated
    • Useful
    • Solid
    1. Cell Biology
    2. Chromosomes and Gene Expression

    Chromosomes: Exploring a crossroads in the aging process

    Kiyan Shabestary, Daniel E Gottschling
    Experiments on yeast show that the nuclear pore complex has a central role in the loss of chromosomes associated with aging.
    Version of Record
    Insight
    1. Cell Biology
    2. Chromosomes and Gene Expression

    Dissociation of the nuclear basket triggers chromosome loss in aging yeast

    Mihailo Mirkovic, Jordan McCarthy ... Yves Barral
    Aging results in remodeling of the nuclear pore complex and leakage of intron-containing pre-mRNA out of the nucleus, altering gene function and mitotic stability of old cells.
    1. Chromosomes and Gene Expression

    Endogenous Real Time Imaging Reveals Dynamic Chromosomal Mobility During Ligand-Mediated Transcriptional Burst Events

    Susan Wang, Thomas Suter ... Michael G Rosenfeld
    Not revised
    Reviewed Preprint v1
    • Important
    • Incomplete
    1. Developmental Biology
    2. Chromosomes and Gene Expression

    Epigenetic delineation of the earliest cardiac lineage segregation by single-cell multi-omics

    Peng Xie, Xu Jiang ... Chengqi Lin
    Revised
    Reviewed Preprint v2
    Updated
    • Useful
    • Inadequate
    1. Chromosomes and Gene Expression

    Distal Gene Expression Governed by Lamins and Nesprins via Chromatin Conformation Change

    Haihui Zhang, Zhengyang Lei ... Peiwu Qin
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Inadequate
    1. Chromosomes and Gene Expression
    2. Cancer Biology

    Degradation of LMO2 in T cell leukaemia results in collateral breakdown of transcription complex partners and causes LMO2-dependent apoptosis

    Naphannop Sereesongsaeng, Carole JR Bataille ... Terry H Rabbitts
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Solid
    1. Chromosomes and Gene Expression
    2. Developmental Biology

    HIF1A-mediated pathways promote euploid cell survival in chromosomally mosaic embryos

    Estefania Sanchez-Vasquez, Marianne E Bronner, Magdalena Zernicka-Goetz
    Aneuploid mosaic mouse embryos require hypoxia for survival, and understanding these pathways may inform new strategies to support embryo viability.

Senior editors

  1. Yamini Dalal
    National Cancer Institute, United States
  2. Adèle L Marston
    University of Edinburgh, United Kingdom
  3. Lori Sussel
    University of Colorado Anschutz Medical Campus, United States
  4. See more editors