Browse our latest Computational and Systems Biology articles

Page 37 of 125
    1. Computational and Systems Biology
    2. Neuroscience

    Principles for coding associative memories in a compact neural network

    Christian Pritz, Eyal Itskovits ... Alon Zaslaver
    A compact neural network can form various associative memories that are encoded in a distributed manner, where each neuron stores different components of the memory.
    1. Computational and Systems Biology
    2. Neuroscience

    Memory: When neurons split the load

    Itamar Lev, Manuel Zimmer
    Various aspects of olfactory memory are represented as modulated responses across different classes of neurons in C. elegans.
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    1. Computational and Systems Biology
    2. Immunology and Inflammation

    Improved T cell receptor antigen pairing through data-driven filtering of sequencing information from single cells

    Helle Rus Povlsen, Amalie Kai Bentzen ... Morten Nielsen
    A bioinformatics approach shows how to reduce noise in single-cell TCR-pMHC specificity data while retaining sensitivity toward cross-binding events to facilitate investigation of the rules governing TCR-pMHC binding.
    1. Computational and Systems Biology
    2. Neuroscience

    Metabolic activity organizes olfactory representations

    Wesley W Qian, Jennifer N Wei ... Alexander B Wiltschko
    Metabolic activity across all living things represents an organizing principle for the sense of smell in humans and animals.
    1. Computational and Systems Biology
    2. Developmental Biology

    Patterning precision under non-linear morphogen decay and molecular noise

    Jan Andreas Adelmann, Roman Vetter, Dagmar Iber
    Statistical analysis of morphogen gradients indicates that non-linear morphogen decay does not lead to significantly increased patterning precision, and in fact, the opposite is observed far from the source.
    1. Cancer Biology
    2. Computational and Systems Biology

    Pan-cancer association of DNA repair deficiencies with whole-genome mutational patterns

    Simon Grund Sørensen, Amruta Shrikhande ... Jakob Skou Pedersen
    Deficiencies of several DNA damage response genes can be predicted by their association with genome-wide mutation patterns.
    1. Computational and Systems Biology

    Longitudinal fundus imaging and its genome-wide association analysis provide evidence for a human retinal aging clock

    Sara Ahadi, Kenneth A Wilson ... Ali Bashir
    Deep learning on fundus images provides a non-invasive, short time-scale biological aging clock that successfully identifies aging genes validated in a fly model.
    1. Computational and Systems Biology
    2. Ecology

    Emergent regulation of ant foraging frequency through a computationally inexpensive forager movement rule

    Lior Baltiansky, Guy Frankel, Ofer Feinerman
    Rather than complex decisions, it is the motion of individuals that allows for collective foraging regulation in ant colonies.
    1. Plant Biology
    2. Computational and Systems Biology

    The photosystem I supercomplex from a primordial green alga Ostreococcus tauri harbors three light-harvesting complex trimers

    Asako Ishii, Jianyu Shan ... Jun Minagawa
    The structure of the photosystem I (PSI) supercomplex in Ostreococcus tauri has revealed a unique hybrid of both plant-type and green algal-type PSI supercomplexes with three Lhcp trimers located at the ‘state 2’ position.
    1. Computational and Systems Biology
    2. Epidemiology and Global Health

    Bias in nutrition-health associations is not eliminated by excluding extreme reporters in empirical or simulation studies

    Nao Yamamoto, Keisuke Ejima ... Andrew W Brown
    Elimination of extreme reporters using Goldberg cutoffs does not always produce unbiased estimates of associations between nutrition intakes and health outcomes.