Browse our latest Developmental Biology articles

Qki-Srebp2–mediated cholesterol biosynthesis is indispensable for myelinogenesis during early brain development.

Wnt distribution is regulated by a dynamic exchange of its abundant scaffold-bound and rare freely diffusing populations, providing insights into a conceived dilemma of speed and stability of tissue patterning.

Unlike in early embryonic development, injured spinal cord and muscle in Xenopus laevis larvae recruit non-canonical Hedgehog signaling essential for their regeneration, while repressing Gli transcriptional activity.

Radial patterns of cell morphology in the Drosophila larval wing emerge through mechanosensitive dynamics of cell polarity.

Loss of the transcription factor Rreb1 results perturbs epithelial architecture during mouse development resulting in invasive cell behaviors, severe cardiovascular defects, and embryonic lethality.

HDAC SUMOylation promotes the association of other chromatin remodeling factors with the nuclear Argonaute WAGO-9, which is required for de novo heterochromatin silencing.

The apparently incompatible functions of the Hedgehog co-receptor Ihog in homophilic adhesion and ligand binding cooperate in Hh transport and reception.

Artificial selection for increased tibia length in mice made their skulls longer, narrower, and flatter, suggesting that even distant skeletal regions can evolve as correlated responses to selection acting locally.

Axon guidance molecules DCC and NTN1 regulate astroglial-mediated interhemispheric remodelling required for corpus callosum formation in humans and mice.

Developing T cells whose TCRs have relatively low reactivity experience very brief TCR signaling events, experience delayed positive selection, and retaina preselection gene expression signature as they mature.