Browse our latest Developmental Biology articles

Page 84 of 213
    1. Cell Biology
    2. Developmental Biology

    The GNU subunit of PNG kinase, the developmental regulator of mRNA translation, binds BIC-C to localize to RNP granules

    Emir E Avilés-Pagán, Masatoshi Hara, Terry L Orr-Weaver
    The Drosophila PNG kinase controls mRNA translation at the oocyte-to-embryo transition, and its GNU activating subunit is shown here to bind translational repressors and be a component of RNP granules.
    1. Developmental Biology

    Chondrocytes in the resting zone of the growth plate are maintained in a Wnt-inhibitory environment

    Shawn A Hallett, Yuki Matsushita ... Noriaki Ono
    Slow-cycling chondrocytes are maintained in a Wnt-inhibitory environment within the resting zone, unraveling a novel mechanism regulating maintenance and differentiation of parathyroid hormone-related protein (PTHrP)-expressing skeletal stem cells of the postnatal growth plate.
    1. Cancer Biology
    2. Developmental Biology

    E2F/Dp inactivation in fat body cells triggers systemic metabolic changes

    Maria Paula Zappia, Ana Guarner ... Maxim V Frolov
    The E2F/Dp transcription factors, which are key cell cycle regulators, can also mediate the regulation of carbohydrate metabolism in larva by controlling both systemic trehalose homeostasis and fat storage.
    1. Developmental Biology
    2. Genetics and Genomics

    Somatic aging pathways regulate reproductive plasticity in Caenorhabditis elegans

    Maria C Ow, Alexandra M Nichitean, Sarah E Hall
    Somatic aging and germline RNAi pathways promote inheritance of ancestral starvation memory through reallocation of fat storage in Caenorhabditis elegans.
    1. Cell Biology
    2. Developmental Biology

    Reduced synchroneity of intra-islet Ca2+ oscillations in vivo in Robo-deficient β cells

    Melissa T Adams, JaeAnn M Dwulet ... Barak Blum
    Synchronized β cell response to glucose is lost concomitant with loss of islet architecture in Robo-deficient islets of Langerhans in vivo.
    1. Developmental Biology
    2. Evolutionary Biology

    Cortex cis-regulatory switches establish scale colour identity and pattern diversity in Heliconius

    Luca Livraghi, Joseph J Hanly ... Chris D Jiggins
    The evolution of a butterfly mimetic phenotype is driven by modular cis-regulstory switches controlling a ‘hotspot’ gene.
    1. Developmental Biology

    Pak1 and PP2A antagonize aPKC function to support cortical tension induced by the Crumbs-Yurt complex

    Cornelia Biehler, Katheryn E Rothenberg ... Patrick Laprise
    Cell biology analyses in Drosophila epithelial tissues reveal novel mechanisms connecting epithelial polarity proteins with Myosin-dependent cell contractility.
    1. Computational and Systems Biology
    2. Developmental Biology

    Control of tissue development and cell diversity by cell cycle-dependent transcriptional filtering

    Maria Abou Chakra, Ruth Isserlin ... Gary D Bader
    A mathematical model predicts that cell cycle duration acts as a transcriptional filter and directly affects cell diversity in early eukaryotic development.
    1. Developmental Biology
    2. Stem Cells and Regenerative Medicine

    Fish primary embryonic pluripotent cells assemble into retinal tissue mirroring in vivo early eye development

    Lucie Zilova, Venera Weinhardt ... Joachim Wittbrodt
    Fish-derived pluripotent cells instinctively form retinal tissue recapitulating key steps of early eye development.
    1. Cell Biology
    2. Developmental Biology

    Single-cell RNA-seq analysis reveals penaeid shrimp hemocyte subpopulations and cell differentiation process

    Keiichiro Koiwai, Takashi Koyama ... Ryuji Kawano
    Single-cell mRNA sequencing on hemocytes of penaeid shrimp revealed six types of hemocytes, type markers, differentiation pathways, and different immune roles among these subpopulations based on their transcriptional profiles.