The first overview of fitness interactions within a species provides information how genetic interactions and ecology combine together to determine trait evolution.
Evolutionary adaptation to a constitutive perturbation of DNA replication reveals that adaptive mutations in three conserved pathways interact to restore faithful chromosome replication and segregation.
Julia M Flynn, Ammeret Rossouw ... Daniel NA Bolon
Environmental conditions strongly impact the fitness effects of Hsp90, resulting in the selection of Hsp90 sequences in nature that are robust to a variety of stressful conditions.
Corinne von Känel, Sergio A Muñoz-Gómez ... Andre Schneider
Mitochondrial inner membrane translocation of presequence-containing proteins by the single bifunctional TIM complex of T. brucei requires an non-canonical J domain-containing protein.
Shared complexities of backbone segmentation between cartilaginous fishes and tetrapods originate much earlier in vertebrate evolution than previously thought.
Isolation of a gokushovirus capable of lysogenizing enterobacteria challenges previous notions about the biology of the most prolific phages within the Microviridae and facilitates experimental study in a model organism.
Binshuang Li, Ryan D Bickel ... Jennifer A Brisson
The application of long-read sequencing to the pea aphid wing dimorphism system reveals genomic structural divergence as a genetic mechanism of adaptation.
Nicholas James Strausfeld, Gabriella Hanna Wolff, Marcel Ethan Sayre
Demonstrating extreme diversity across crustaceans while contrasting with evolutionary stability in insects, mushroom body homologues further underpin the unity of Pancrustacea and shed new light on arthropod brain evolution.