Browse our latest Genetics and Genomics articles

Page 108 of 143
    1. Cell Biology
    2. Genetics and Genomics

    Protein Homeostasis: How chloroplasts protect themselves from unfolded proteins

    Felix Kessler, Paolo Longoni
    A genetic screen has identified the first signaling component of the unfolded protein response in chloroplasts.
    Version of Record
    Insight
    1. Genetics and Genomics
    2. Neuroscience

    Dissection of central clock function in Drosophila through cell-specific CRISPR-mediated clock gene disruption

    Rebecca Delventhal, Reed M O'Connor ... Mimi Shirasu-Hiza
    Through novel, cell-specific CRISPR tools to disrupt molecular clock genes, it was revealed that circadian rhythms are coordinated through a network, rather than by the clock of 'master regulatory' neurons.
    1. Evolutionary Biology
    2. Genetics and Genomics

    The yellow gene influences Drosophila male mating success through sex comb melanization

    Jonathan H Massey, Daayun Chung ... Patricia J Wittkopp
    Melanization of a secondary sexual structure facilitates male mating success in Drosophila.
    1. Cell Biology
    2. Genetics and Genomics

    NHR-14 loss of function couples intestinal iron uptake with innate immunity in C. elegans through PQM-1 signaling

    Malini Rajan, Cole P Anderson ... Elizabeth A Leibold
    Nuclear receptor NHR-14 regulates the subcellular localization of the zinc transcription factor PQM-1 to coordinate innate immunity with iron sequestration during pathogen infection in C. elegans..
    1. Genetics and Genomics
    2. Neuroscience

    A scalable platform for the development of cell-type-specific viral drivers

    Sinisa Hrvatin, Christopher P Tzeng ... Michael E Greenberg
    Highly paralleled functional evaluation of enhancer activity in single cells generates new cell-type-specific tools with broad medical and scientific applications.
    1. Evolutionary Biology
    2. Genetics and Genomics

    Sex-specific transcriptomic responses to changes in the nutritional environment

    M Florencia Camus, Matthew DW Piper, Max Reuter
    Male and female Drosophila share core metabolic responses to different nutritional environments, but show opposing patterns of nutrient-dependent reproductive regulation.
    1. Evolutionary Biology
    2. Genetics and Genomics

    Reproduction: How flies turn food into progeny

    Thomas Flatt
    Sex-optimal diets have different effects on gene expression in female and male flies.
    Version of Record
    Insight
    1. Evolutionary Biology
    2. Genetics and Genomics

    A de novo evolved gene in the house mouse regulates female pregnancy cycles

    Chen Xie, Cemalettin Bekpen ... Diethard Tautz
    A female specifically expressed new protein-coding gene that has emerged out of non-coding sequences without detectable signatures of adaptive evolution affects female pregnancy cycles.
    1. Genetics and Genomics

    Large, three-generation human families reveal post-zygotic mosaicism and variability in germline mutation accumulation

    Thomas A Sasani, Brent S Pedersen ... Aaron R Quinlan
    Rates of germline mutation accumulation are highly variable across families of similar genetic ancestry, and post-zygotic mosaicism is a substantial source of de novo mutations.
    1. Developmental Biology
    2. Genetics and Genomics

    Extensive intraspecies cryptic variation in an ancient embryonic gene regulatory network

    Yamila N Torres Cleuren, Chee Kiang Ewe ... Joel H Rothman
    Quantitative genetic analyses reveal remarkably broad genetic variation underlies the requirement for two critical regulatory inputs into a core embryonic gene regulatory network within one animal species.