Browse our latest Genetics and Genomics articles

R-spondin3 global haplo-insufficiency or its deletion in pre-osteoblasts lead to gain of bone mass in the appendicular skeleton with no or opposite phenotype in the axial skeleton.

Sloth1 and Sloth2 are two mitochondrial peptides that are translated from one transcript and are important for neuronal function in Drosophila.

Prospective, cross-sectional, and intra-twin study designs identify skewed X chromosome inactivation is associated with cardiovascular disease risk and future cancer diagnosis in the TwinsUK population cohort.

The identification of alternative splicing targets and upstream RNA-binding proteins that underlie EMT and metastasis in colon cancer stratifies patients according to their overall survival and provide new insights on the function of specific isoforms along the migrating cancer stem cell sequence.

Comprehensive genome-wide associations studies in flies identify new genes and pathways critical for heart development and function and display relevant overlap with human genetic risks related to cardiac performance.

Large-scale, allele-resolved mapping of cis-regulatory function in F₁-hybrid mice reveals sequence determinants that control transcription factor binding and enhancer activity in native chromatin context.

Locally activatable bioluminescence (LABL) is a genetically encoded reporter that allows real time, in vivo measurement of distinct clocks in different cells and tissues in Drosophila.

Animal models reveal that mitochondrial complex I is dispensable for homeostatic functions of the mouse liver.

Large-scale monitoring of Anopheles populations benefits from a robust and accurate species identification and plasmodium detection method that is applicable to the entire genus.

Parallel changes in organismal evolution can be observed even with disparate genomic changes due to similarity in functional outcomes, such as changes in molecular phenotypes like gene expression patterns.