Genetics and Genomics

Latest articles

1. 1. Genetics and Genomics

   Chromatin accessibility variation provides insights into missing regulation underlying immune-mediated diseases

   Raehoon Jeong, Martha L Bulyk
2. 1. Genetics and Genomics
   2. Neuroscience

   Single-cell transcriptome sequencing for opening the blood-brain barrier through specific mode electroacupuncture stimulation

   Congcong Ma, Zhaoxing Jia ... Xianming Lin
3. 1. Genetics and Genomics
   2. Neuroscience

   Aging: Unlocking the longevity code with stress

   Loren Cocciolone, Valeria Uvarova, Patricija van Oosten-Hawle

   Manipulating the neuronal pathway responsible for the hypoxic stress response in the worm C. elegans leads to an increase in lifespan.
4. 1. Epidemiology and Global Health
   2. Genetics and Genomics

   Understanding the global rise of artemisinin resistance: Insights from over 100,000 Plasmodium falciparum samples

   Andrew J Balmer, Nina FD White ... Cristina Ariani

   Spatiotemporal analysis of global kelch13 surveillance data reveals that artemisinin resistance is increasing in East Africa, mirroring patterns previously observed in Southeast Asia.
5. 1. Genetics and Genomics

   Mapping of in vivo cleavage sites uncovers a major role for yeast RNase III in regulating protein-coding genes

   Lee-Ann Notice-Sarpaning, Mathieu Catala ... Ambro van Hoof
6. 1. Genetics and Genomics
   2. Neuroscience

   Phenotypic impact of individual conserved neuronal microexons and their master regulators in zebrafish

   Laura Lopez-Blanch, Cristina Rodríguez-Marin ... Manuel Irimia
7. 1. Genetics and Genomics
   2. Microbiology and Infectious Disease

   Non-cognate immunity proteins provide broader defenses against interbacterial effectors in microbial communities

   Abigail Knecht, Denise Sirias ... Karine A Gibbs

   A biochemical and bioinformatics approach shows how T6SS immunity proteins bind to and neutralize a range of non-cognate effectors, which is critical for promoting bacterial fitness in mixed-strain environments.
8. 1. Developmental Biology
   2. Genetics and Genomics

   Nup107 is a crucial regulator of torso-mediated metamorphic transition in Drosophila melanogaster

   Jyotsna Kawadkar, Pradyumna Ajit Joshi, Ram Kumar Mishra
9. 1. Genetics and Genomics
   2. Neuroscience

   Steady-state neuron-predominant LINE-1 encoded ORF1p protein and LINE-1 RNA increase with aging in the mouse and human brain

   Tom Bonnifet, Sandra Sinnassamy ... Julia Fuchs

   LINE-1-encoded ORF1p is widely expressed in neurons, increases with age, and engages neuron-specific protein partners, revealing a dynamic role for retrotransposons in brain physiology and aging.
10. 1. Genetics and Genomics
    2. Neuroscience

    Starvation transforms signal encoding in C. elegans thermoresponsive neurons and suppresses heat avoidance via bidirectional glutamatergic and peptidergic signaling

    Saurabh Thapliyal, Dominique A Glauser