Genomics and Evolutionary Biology

eLife publishes research spanning adaptation, morphology, bioinformatics and comparative genomics. Decisions are made by journal editors who are active researchers in the fields of genomics and/or evolutionary biology.

Latest articles

    1. Genomics and Evolutionary Biology
    2. Microbiology and Infectious Disease

    Exploiting CRISPR-Cas to manipulate Enterococcus faecalis populations

    Karthik Hullahalli et al.
    Conflicts between CRISPR-Cas systems and antibiotic resistance plasmids can be exploited to selectively eliminate antibiotic resistance from Enterococcus faecalis populations.
    Research Article Updated
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    1. Genomics and Evolutionary Biology
    2. Microbiology and Infectious Disease

    Parallel evolution of influenza across multiple spatiotemporal scales

    Katherine S Xue et al
    Influenza evolution within infected hosts recapitulates many evolutionary dynamics observed at the global scale.
    Short Report
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    1. Genes and Chromosomes
    2. Genomics and Evolutionary Biology

    Simultaneous measurement of chromatin accessibility, DNA methylation, and nucleosome phasing in single cells

    Sebastian Pott
    Establishment of a method that measures multiple aspects of chromatin organization in single cells with the possible application to study regulatory processes in heterogeneous samples.
    Tools and Resources
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    1. Epidemiology and Global Health
    2. Genomics and Evolutionary Biology

    The Anopheles gambiae 2La chromosome inversion is associated with susceptibility to Plasmodium falciparum in Africa

    Michelle M Riehle et al.
    A common chromosome inversion in African malaria mosquito (Anopheles gambiae) is associated with differences in malaria infection, adult resting behavior and ecology, and may aid the most efficient vectors to evade malaria control.
    Research Article
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    1. Genomics and Evolutionary Biology

    On the mechanistic nature of epistasis in a canonical cis-regulatory element

    Mato Lagator et al
    Thermodynamic framework accurately predicts the sign of epistasis and its environment dependence for a canonical cis-regulatory element.
    Research Article Updated
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    1. Genes and Chromosomes
    2. Genomics and Evolutionary Biology

    wtf genes are prolific dual poison-antidote meiotic drivers

    Nicole L Nuckolls et al
    Selfish wtf meiotic drive genes use overlapping transcripts to encode both a trans-acting poison to kill gametes that do not inherit the gene and a gamete-autonomous antidote to specifically rescue the gametes that do.
    Research Article
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    1. Genes and Chromosomes
    2. Genomics and Evolutionary Biology

    Heredity: The gene family that cheats Mendel

    J Dylan Shropshire, Antonis Rokas
    Some alleles of the wtf gene family can increase their chances of spreading by using poisons to kill other alleles, and antidotes to save themselves.
    Insight
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    1. Genomics and Evolutionary Biology

    A large gene family in fission yeast encodes spore killers that subvert Mendel’s law

    Wen Hu et al
    Two members of a large fission yeast (Schizosaccharomyces pombe) gene family are shown to act as spore killers that enhance their own transmission into progenies by impeding the maturation of spores not inheriting them.
    Research Article
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