Genetics and Genomics

Latest articles

1. 1. Genetics and Genomics

   SERBP1 interacts with PARP1 and is present in PARylation-dependent protein complexes regulating splicing, cell division, and ribosome biogenesis

   Kira Breunig, Xiufen Lei ... Luiz O. F. Penalva
2. 1. Genetics and Genomics
   2. Epidemiology and Global Health

   Systematic evaluation of multifactorial causal associations for Alzheimer’s disease and an interactive platform based on Mendelian randomization analysis — MRAD

   Tianyu Zhao, Hui Li ... Li Chen
3. 1. Chromosomes and Gene Expression
   2. Genetics and Genomics

   Evolutionary Adaptation of an HP1-protein Chromodomain Integrates Chromatin and DNA Sequence Signals

   Lisa Baumgartner, Jonathan J. Ipsaro ... Julius Brennecke
4. 1. Genetics and Genomics
   2. Cancer Biology

   Circulating Small Extracellular Vesicle RNA Profiling for the Detection of T1a stage Colorectal Cancer and Precancerous Advanced Adenoma

   Li Min, Fanqin Bu ... Shutian Zhang
5. 1. Genetics and Genomics
   2. Neuroscience

   The neuron-specific IIS/FOXO transcriptome in aged animals reveals regulatory mechanisms of cognitive aging

   Yifei Weng, Shiyi Zhou ... Coleen T Murphy

   Neuron-specific sequencing of aged wild-type, daf-2, and daf-16;daf-2 mutants revealed transcriptomic changes with age, and in longevity mutants, putative neuroprotective genes are upregulated, which are required for prolonged cognitive functions.
6. 1. Genetics and Genomics

   Dimeric ^R25CPTH(1–34) Activates the Parathyroid Hormone-1 Receptor in vitro and Stimulates Bone Formation in Osteoporotic Female Mice

   Minsoo Noh, Xiangguo Che ... Sihoon Lee
7. 1. Genetics and Genomics

   Discovering non-additive heritability using additive GWAS summary statistics

   Samuel Pattillo Smith, Gregory Darnell ... Lorin Crawford

   Computational analysis reveals that additive summary statistics from genome-wide association studies can provide evidence of non-additive heritability in complex traits.
8. 1. Evolutionary Biology
   2. Genetics and Genomics

   Copy number variation and population-specific immune genes in the model vertebrate zebrafish

   Yannick Schäfer, Katja Palitzsch ... Jaanus Suurväli

   As a result of frequent gene duplication and haplotypic variation, a family of immune genes in the model vertebrate zebrafish has thousands of gene copies that are population- or individual-specific.
9. 1. Developmental Biology
   2. Genetics and Genomics

   Caspar determines primordial germ cell identity in Drosophila melanogaster

   Subhradip Das, Sushmitha Hegde ... Girish S Ratnaparkhi
10. 1. Computational and Systems Biology
    2. Genetics and Genomics

    Discovery of runs-of-homozygosity diplotype clusters and their associations with diseases in UK Biobank

    Ardalan Naseri, Degui Zhi, Shaojie Zhang