Genomics and Evolutionary Biology

eLife publishes research spanning adaptation, morphology, bioinformatics and comparative genomics. Decisions are made by journal editors who are active researchers in the fields of genomics and/or evolutionary biology.

Latest articles

    1. Epidemiology and Global Health
    2. Genomics and Evolutionary Biology

    The Anopheles gambiae 2La chromosome inversion is associated with susceptibility to Plasmodium falciparum in Africa

    Michelle M Riehle et al.
    A common chromosome inversion in African malaria mosquito (Anopheles gambiae) is associated with differences in malaria infection, adult resting behavior and ecology, and may aid the most efficient vectors to evade malaria control.
    Research Article
    Available as full, typeset article htmlAvailable as authors' accepted manuscript pdf
    1. Genomics and Evolutionary Biology

    On the mechanistic nature of epistasis in a canonical cis-regulatory element

    Mato Lagator et al
    Thermodynamic framework accurately predicts the sign of epistasis and its environment dependence for a canonical cis-regulatory element.
    Research Article Updated
    Available as full, typeset article htmlAvailable as authors' accepted manuscript pdf
    1. Genes and Chromosomes
    2. Genomics and Evolutionary Biology

    Heredity: The gene family that cheats Mendel

    J Dylan Shropshire, Antonis Rokas
    Some alleles of the wtf gene family can increase their chances of spreading by using poisons to kill other alleles, and antidotes to save themselves.
    Insight
    Available as full, typeset article htmlAvailable as authors' accepted manuscript pdf
    1. Genes and Chromosomes
    2. Genomics and Evolutionary Biology

    wtf genes are prolific dual poison-antidote meiotic drivers

    Nicole L Nuckolls et al
    Selfish wtf meiotic drive genes use overlapping transcripts to encode both a trans-acting poison to kill gametes that do not inherit the gene and a gamete-autonomous antidote to specifically rescue the gametes that do.
    Research Article
    Available as full, typeset article htmlAvailable as authors' accepted manuscript pdf
    1. Genomics and Evolutionary Biology

    A large gene family in fission yeast encodes spore killers that subvert Mendel’s law

    Wen Hu et al
    Two members of a large fission yeast (Schizosaccharomyces pombe) gene family are shown to act as spore killers that enhance their own transmission into progenies by impeding the maturation of spores not inheriting them.
    Research Article
    Available as full, typeset article htmlAvailable as authors' accepted manuscript pdf
    1. Genes and Chromosomes
    2. Genomics and Evolutionary Biology

    The dynamic three-dimensional organization of the diploid yeast genome

    Seungsoo Kim et al
    Yeast homologous chromosomes exhibit condition-specific mitotic pairing at both global and local scales.
    Research Article Updated
    Available as full, typeset article htmlAvailable as authors' accepted manuscript pdf