Genetics and Genomics

Genetics and Genomics

eLife reviews research including the genetic basis of health and disease, epigenetics, genomics, medical genetics, genetic epidemiology, and population genetics. Learn more about what we review and sign up for the latest research.
Illustration by Davide Bonazzi

Latest articles

    1. Genetics and Genomics

    Identification of a somatic H3K23me3 methyltransferase SET-19 in C. elegans

    Mingjing Xu, Zixue Fan ... Xuezhu Feng
    Not revised
    Reviewed Preprint v1
    • Fundamental
    • Compelling
    1. Genetics and Genomics
    2. Computational and Systems Biology

    Optics-free reconstruction of shapes, images and volumes with DNA barcode proximity graphs

    Hanna Liao, Sanjay Kottapalli ... Sanjay Srivatsan
    Not revised
    Reviewed Preprint v1
    • Important
    • Convincing
    1. Genetics and Genomics
    2. Evolutionary Biology

    The causes and consequences of human-specific DNA methylation

    Zhenzhen Ma, Alexander L Starr ... Hunter B Fraser
    Not revised
    Reviewed Preprint v1
    • Important
    • Compelling
    • Incomplete
    1. Genetics and Genomics
    2. Immunology and Inflammation

    GM-CSF regulates ILC states and myeloid cell signaling during ulceration in Crohn’s disease

    Joshua K Morrison, Ksenija Sabic ... Ling-shiang Chuang
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Incomplete
    1. Genetics and Genomics
    2. Neuroscience

    Oxytocin receptor controls promiscuity and development in prairie voles

    Ruchira Sharma, Kristen M Berendzen ... Devanand S Manoli
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Solid
    1. Genetics and Genomics
    2. Medicine

    Point of View: Teaching early-career researchers how to respond to peer reviewers

    Eric Kalkhoven, Manon Kluijtmans
    Responding to reports from peer reviewers is a crucial part of scientific publishing, but early-career researchers are rarely taught about this process.
    1. Genetics and Genomics
    2. Neuroscience

    Morphine regulates astrocyte transcriptional dynamics in the ventral tegmental area by stimulation of glucocorticoid signaling

    Jennifer J Tuscher, Angela Cleere ... Jeremy J Day
    Not revised
    Reviewed Preprint v1
    • Important
    • Convincing
    1. Cell Biology
    2. Genetics and Genomics

    Mechanistic insights into transcriptional regulation of ARHGAP36 expression identify a factor predictive of neuroblastoma survival

    Serhiy Havrylov, Armin M Gamper, Ordan J Lehmann
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Solid
    1. Developmental Biology
    2. Genetics and Genomics

    Single-cell co-mapping reveals relationship between chromatin state and gene expression in early zebrafish development

    Vivek Bhardwaj, Alberto Griffa ... Alexander van Oudenaarden
    A robust and quantitative map links chromatin modification and gene expression of cells during zebrafish embryogenesis.
    1. Developmental Biology
    2. Genetics and Genomics

    In situ mutational screening and CRISPR interference define apterous cis-regulatory inputs during compartment boundary formation

    Gustavo Aguilar, Michèle Sickmann ... Martin Müller
    Revised
    Reviewed Preprint v3
    Updated
    • Important
    • Compelling
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Highlights

    1. Genetics and Genomics
    2. Medicine

    How to respond to peer reviewers

    Eric Kalkhoven, Manon Kluijtmans
    1. Developmental Biology
    2. Genetics and Genomics

    Written out of history

    Lisa M Thomann, Julie Batut
    1. Chromosomes and Gene Expression
    2. Genetics and Genomics

    Chromosomes: Finding a role for non-coding DNA in trypanosomes

    Markus R Schmidt

Senior editors

  1. Kathryn Cheah
    The University of Hong Kong, Hong Kong SAR China
  2. Yamini Dalal
    National Cancer Institute, United States
  3. Alan Moses
    University of Toronto, Canada
  4. See more editors