Human Biology and Medicine

Human Biology and Medicine

eLife publishes research in clinical and translational research, human genetics, cancer, diabetes and developmental disorders. Learn more about what we publish and sign up for the latest research.
Illustration by Davide Bonazzi

Latest articles

    1. Human Biology and Medicine

    A synthetic dataset primer for the biobehavioural sciences to promote reproducibility and hypothesis generation

    Daniel S Quintana
    Sharing synthetic datasets that mimic original datasets that could not otherwise be made publicly available can help ensure reproducibility and facilitate data exploration while maintaining participant privacy.
    1. Human Biology and Medicine

    Meta-Research: Reader engagement with medical content on Wikipedia

    Lauren A Maggio et al.
    Readers of health and medicine Wikipedia pages are more likely to hover over and view footnotes than other readers, but less likely to view the hyperlinked sources in these footnotes.
    1. Human Biology and Medicine
    2. Neuroscience

    Opioids depress breathing through two small brainstem sites

    Iris Bachmutsky et al.
    Opioids stop breathing during overdose by silencing two small brain sites, with just 140 neurons in the breathing rhythm generator exerting the key effect.
    1. Human Biology and Medicine
    2. Immunology and Inflammation

    SLAMF6​ deficiency augments tumor killing and skews toward an effector phenotype revealing it as a novel T cell checkpoint

    Emma Hajaj et al.
    SLAMF6 is an inhibitory checkpoint of T cells, the lack of which leads to better tumor control, suggesting a new immunotherapy target.
    1. Human Biology and Medicine
    2. Immunology and Inflammation

    p16 deficiency attenuates intervertebral disc degeneration by adjusting oxidative stress and nucleus pulposus cell cycle

    Hui Che et al.
    A novel IVDD mechanism that involves p16 is demonstrated and theoretical evidence is provided for effective methods to downregulate p16 and so reverse IVDD.

Highlights

    1. Human Biology and Medicine

    Medical content on Wikipedia

    Lauren A Maggio et al.

Senior editors

  1. Matthias Barton
    University of Zurich, Switzerland
  2. Neil Ferguson
    Imperial College London, United Kingdom
  3. Jos WM van der Meer
    Radboud University Medical Centre, Netherlands
  4. See more editors