Medicine

Medicine

eLife reviews translational, clinical and health policy research in all areas of medicine. Learn more about what we review and sign up for the latest research.
Illustration by Davide Bonazzi

Latest articles

    1. Medicine

    Cell-autonomous and non-cell-autonomous effects of Arginase 2 on cardiac aging

    Duilio M Potenza, Xin Cheng ... Xiu-Fen Ming
    Arginase 2 in macrophages promotes cardiac aging phenotype via paracrine release of IL-1β.
    1. Medicine

    Addressing cultural and knowledge barriers to enable preclinical sex inclusive research

    Brianna N Gaskill, Benjamin Phillips ... Natasha A Karp
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Solid
    1. Computational and Systems Biology
    2. Medicine

    Critique of impure reason: Unveiling the reasoning behaviour of medical large language models

    Shamus Zi Yang Sim, Tyrone Chen
    A survey of reasoning behaviour in medical large language models uncovers emerging trends, highlights open challenges, and introduces theoretical frameworks that enhance reasoning behaviour transparency, ultimately fostering greater trust among clinicians, developers, and patients in their deployment.
    1. Medicine
    2. Neuroscience

    Functional Muscle Networks as Biomarkers of Post-Stroke Motor Impairment and Therapeutic Responsiveness

    David O’Reilly, Giorgia Pregnolato ... Giacomo Severini
    Not revised
    Reviewed Preprint v1
    • Important
    • Incomplete
    1. Medicine

    Mid-zone hepatocytes trade proliferation for survival via Atf4-Chop axis in early acute liver injury

    Yaying Zhu, Chengxiang Deng ... Zhao Shan
    Not revised
    Reviewed Preprint v1
    • Important
    • Incomplete
    1. Cell Biology
    2. Medicine

    Uncovering Shared and Tissue-Specific Molecular Adaptations to Intermittent Fasting in Liver, Brain, and Muscle

    Yibo Fan, Senuri De Silva ... Thiruma V Arumugam
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
    1. Medicine
    2. Neuroscience

    GPR30 in spinal cholecystokinin-positive neurons modulates neuropathic pain

    Qing Chen, Hui Wu ... Xinzhong Chen
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Convincing
    1. Cancer Biology
    2. Medicine

    Monitoring circulating cell-free HPV DNA in metastatic or recurrent cervical cancer: clinical significance and treatment implications

    Zhuomin Yin, Tao Feng ... Hanmei Lou
    HPV cfDNA is a highly effective tumor marker for monitoring disease progression and treatment response in HPV-positive cervical cancer, offering valuable insights for guiding clinical decisions in precision medicine.

Senior editors

  1. Tony Ng
    King's College London, United Kingdom
  2. Jonathan Roiser
    University College London, United Kingdom
  3. Wei Yan
    Washington State University, United States
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