Immunology and Inflammation

Immunology and Inflammation

eLife reviews research spanning allergy, immunity and immunoregulation, inflammation and T-cell receptor signalling. Learn more about what we review and sign up for the latest research.
Illustration by Davide Bonazzi

Latest articles

    1. Immunology and Inflammation

    DGKα and ζ Deficiency Causes Regulatory T-Cell Dysregulation, Destabilization, and Conversion to Pathogenic T-Follicular Helper Cells to Trigger IgG1-Predominant Autoimmunity

    Lei Li, Hongxiang Huang ... Xiao-Ping Zhong
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Solid
    1. Immunology and Inflammation

    Synthetic auxotrophy reveals metabolic regulation of plasma cell generation, affinity maturation, and cytokine receptor signaling

    Sung Hoon Cho, Shawna K Brookens ... Mark R Boothby
    Not revised
    Reviewed Preprint v1
    • Important
    • Solid
    1. Immunology and Inflammation
    2. Medicine

    A pair of congenic mice for imaging of transplants by positron emission tomography using anti-transferrin receptor nanobodies

    Thomas Balligand, Claire Carpenet ... Maarten Dewilde
    Two radio-labeled nanobodies and a single knock-in mouse model suffice to track the biodistribution of various unmodified cell-types in live mice by PET/CT.
    1. Immunology and Inflammation

    Xcr1+ type 1 conventional dendritic cells are essential mediators for atherosclerosis progression

    Tianhan Li, Liaoxun Lu ... Lichen Zhang
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Convincing
    1. Immunology and Inflammation
    2. Cancer Biology

    An Evaluation of the Tumor Microenvironment through CALR, IL1R1, IFNB1, and IFNG to Assess Prognosis and Immunotherapy Response in Bladder Cancer Patients

    Lilong Liu, Zhenghao Liu ... Zheng Liu
    Revised
    Reviewed Preprint v2
    Updated
    • Useful
    • Incomplete
    1. Immunology and Inflammation

    CD81+ senescent-like fibroblasts exaggerate inflammation and activate neutrophils via C3/C3aR1 axis in periodontitis

    Liangliang Fu, Chenghu Yin ... Haibin Xia
    Targeting CD81+ fibroblasts–neutrophils axis provides a new strategy for periodontitis treatment.
    1. Immunology and Inflammation
    2. Cancer Biology

    The 1000+ mouse project: large-scale spatiotemporal parametrization and modeling of preclinical cancer immunotherapies

    Adam L Kenet, Sooraj Achar ... Grégoire Altan-Bonnet
    Not revised
    Reviewed Preprint v1
    • Fundamental
    • Compelling
    1. Immunology and Inflammation
    2. Evolutionary Biology

    Newly discovered and conserved role of IgM against viral infection in an early vertebrate

    Weiguang Kong, Xinyou Wang ... Zhen Xu
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Solid
    1. Immunology and Inflammation

    Aurora kinase A promotes trained immunity via regulation of endogenous S-adenosylmethionine metabolism

    Mengyun Li, Huan Jin ... Xiaojun Xia
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Solid
    1. Immunology and Inflammation
    2. Microbiology and Infectious Disease

    Trained immunity in the lung

    Elina Idiiatullina, Dane Parker
    Several studies have now demonstrated that trained immunity occurs in the airways to several pathogens and products, while its utility is yet to be determined.
Load more

Highlights

    1. Developmental Biology
    2. Immunology and Inflammation

    A hemocyte atlas for an insect

    Samuel Liegeois, Dominique Ferrandon
    1. Computational and Systems Biology
    2. Immunology and Inflammation

    The immune basis of disease susceptibility

    Ruy M Ribeiro, Luis Graca
    1. Immunology and Inflammation
    2. Microbiology and Infectious Disease

    Parkinson's and innate immunity

    Rebecca L Wallings, Mary K Herrick, Malú Gámez Tansey

Senior editors

  1. Wendy S Garrett
    Wendy S Garrett
    Harvard T.H. Chan School of Public Health, United States
  2. Diane M Harper
    University of Michigan, United States
  3. Joshua T Schiffer
    Fred Hutchinson Cancer Research Center, United States
  4. See more editors