Browse our latest Immunology and Inflammation articles

The splicing factor RNP-6/PUF60 suppresses immunity by modulating host splicing and transcriptional responses to infection.

Interaction mapping of ubiquitin ligase complexes embedded in the endoplasmic reticulum membrane has identified interactors of RNF26 that influence innate immune signalling.

Single-cell RNA sequencing has revealed distinct subpopulations of hemocytes in fruit fly larvae.

Tissue infection by an extracellular pathogen is recapitulated by encasing a bacterial colony within a droplet gel to allow immune cell attack, driving spatially-controlled microbial social behavior.

Experiments in mice provide insights into the immunological mechanisms of action the vaccine adjuvant MF59.

Lymphocyte migration and autoimmunity induction rely on Formin-like 1-mediated actin network remodeling to push the lymphocyte nucleus through restrictive endothelial barriers.

The strength of TCR signalling determines the rate at which cells initiate a tightly coordinated signalling programme, without altering its organization.

A distinct resident macrophage subpopulation that localizes to the adipose stroma and fibrous capsule of the nulliparous mammary gland and to extracellular matrix-enriched stroma surrounding mammary tumors is identified.

Hepatitis C virus evades IRF1-dependent intrinsic antiviral immunity by exploiting cyclophilin A and its regulation of PKR.

The COVID-19 pandemic has clearly demonstrated the need for a global system to monitor the dynamics of susceptibility and immunity, as well as infection, during epidemics and pandemics.