Immunology and Inflammation

Latest articles

1. 1. Immunology and Inflammation
   2. Microbiology and Infectious Disease

   Virus infection is controlled by hematopoietic and stromal cell sensing of murine cytomegalovirus through STING

   Sytse J Piersma et al.

   Cytomegaloviruses are recognized by distinct sensors depending on the infected cell type and together these sensors are essential for viral control and downstream immune responses.
2. 1. Immunology and Inflammation

   Notch and TLR signaling coordinate monocyte cell fate and inflammation

   Jaba Gamrekelashvili et al.

   Notch signaling alters TLR-induced inflammation by skewing monocyte cell fate toward patrolling monocyte differentiation at the expense of macrophage cell fate.
3. 1. Cancer Biology
   2. Immunology and Inflammation

   Osterix-Cre marks distinct subsets of CD45- and CD45+ stromal populations in extra-skeletal tumors with pro-tumorigenic characteristics

   Biancamaria Ricci et al.
4. 1. Computational and Systems Biology
   2. Immunology and Inflammation

   Tailored design of protein nanoparticle scaffolds for multivalent presentation of viral glycoprotein antigens

   George Ueda et al.

   De novo protein nanoparticles were designed from scratch to present viral glycoprotein antigens, providing a systematic way to study the influence of antigen presentation geometry on immune response.
5. 1. Immunology and Inflammation
   2. Microbiology and Infectious Disease

   Chronic ethanol consumption compromises neutrophil function in acute pulmonary Aspergillus fumigatus infection

   Nathalia Luisa Sousa de Oliveira Malacco et al.

   Cell biology analysis demonstrated for the first time the effect of chronic ethanol consumption in neutrophil impaired migration by CXCR2 downregulation and neutrophil function during acute Aspergillus fumigatus infection.
6. 1. Immunology and Inflammation
   2. Neuroscience

   Drainage of inflammatory macromolecules from brain to periphery targets the liver for macrophage infiltration

   Linlin Yang et al.
7. 1. Immunology and Inflammation
   2. Microbiology and Infectious Disease

   High glucose levels increase influenza-associated damage to the pulmonary epithelial-endothelial barrier

   Katina D Hulme et al.

   Hyperglycaemia increases influenza severity by damaging the pulmonary epithelial-endothelial barrier and increasing pulmonary oedema during Influenza A virus infection.
8. 1. Immunology and Inflammation

   Interrogating the recognition landscape of a conserved HIV-specific TCR reveals distinct bacterial peptide cross-reactivity

   Juan L Mendoza et al.

   Potential for specific microbiome-directed, MHC-restricted shaping of a commonly selected HIV-specific CD8+ T cell population was suggested by MHC class I yeast display-based peptide screening approaches.
9. 1. Cell Biology
   2. Immunology and Inflammation

   Mouse T cell priming is enhanced by maturation-dependent stiffening of the dendritic cell cortex

   Daniel Blumenthal et al.
10. 1. Developmental Biology
    2. Immunology and Inflammation

    Estrogen exacerbates mammary involution through neutrophil dependent and independent mechanism

    Chew Leng Lim et al.