Immunology and Inflammation

Immunology and Inflammation

eLife reviews research spanning allergy, immunity and immunoregulation, inflammation and T-cell receptor signalling. Learn more about what we review and sign up for the latest research.
Illustration by Davide Bonazzi

Latest articles

    1. Immunology and Inflammation

    CD81+ senescent-like fibroblasts exaggerate inflammation and activate neutrophils via C3/C3aR1 axis in periodontitis

    Liangliang Fu, Chenghu Yin ... Haibin Xia
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Solid
    1. Immunology and Inflammation

    Acute Lung Injury: The double-edged nature of trained immunity

    Chrissy M Leopold Wager, Larry S Schlesinger
    Trained immunity in alveolar macrophages can lead to damaging lung inflammation, confirming the importance of context in this phenomenon.
    Version of Record
    Insight
    1. Immunology and Inflammation
    2. Medicine

    C-C chemokine receptor 4 deficiency exacerbates early atherosclerosis in mice

    Toru Tanaka, Naoto Sasaki ... Yoshiyuki Rikitake
    CCR4 expression in Tregs is critical for limiting proinflammatory Th1 cell-mediated immune responses and atherosclerosis by maintaining the suppressive and migratory functions of Tregs.
    1. Immunology and Inflammation

    Epidermal Resident Memory T Cell Fitness Requires Antigen Encounter in the Skin

    Eric S Weiss, Toshiro Hirai ... Daniel H Kaplan
    Not revised
    Reviewed Preprint v1
    • Important
    • Convincing
    1. Evolutionary Biology
    2. Immunology and Inflammation

    Current insights into insect immune memory

    Gabriela Krejčová, Adam Bajgar
    Insects possess a remarkable ability to develop innate immune memory, and the mechanisms underlying this process are becoming a central topic in innate immunity research.
    1. Immunology and Inflammation
    2. Neuroscience

    Microglia replacement by ER-Hoxb8 conditionally immortalized macrophages provides insight into Aicardi-Goutières Syndrome neuropathology

    Kelsey M Nemec, Genevieve Uy ... F Chris Bennett
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Exceptional
    1. Immunology and Inflammation
    2. Microbiology and Infectious Disease

    Malnutrition drives infection susceptibility and dysregulated myelopoiesis that persists after refeeding intervention

    Alisa Sukhina, Clemence Queriault ... Will Bailis
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Convincing
    • Incomplete
    1. Immunology and Inflammation

    CD131 contributes to ulcerative colitis pathogenesis by promoting macrophage infiltration

    Zhiyuan Wu, Lindi Liu ... Xiaodong Tan
    CD131 contributes to intestinal inflammation in ulcerative colitis, possibly by promoting the infiltration of macrophages, while targeting CD131 might potentially be a treatment remedy for ulcerative colitis.
    1. Immunology and Inflammation
    2. Microbiology and Infectious Disease

    Doubling dolutegravir dosage reduces the viral reservoir in ART-treated people with HIV

    Céline Fombellida-Lopez, Aurelija Valaitienė ... Gilles Darcis
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Incomplete
    1. Immunology and Inflammation
    2. Neuroscience

    Glia-mediated gut-brain cytokine signaling couples sleep to intestinal inflammation

    Alina Malita, Anne H Skakkebaek ... Kim Rewitz
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Compelling

Senior editors

  1. Wendy S Garrett
    Wendy S Garrett
    Harvard T.H. Chan School of Public Health, United States
  2. Satyajit Rath
    Indian Institute of Science Education and Research (IISER), Pune, India
  3. Joshua T Schiffer
    Fred Hutchinson Cancer Research Center, United States
  4. See more editors