Browse our latest Microbiology and Infectious Disease articles

Page 60 of 172
    1. Microbiology and Infectious Disease
    2. Structural Biology and Molecular Biophysics

    An M protein coiled coil unfurls and exposes its hydrophobic core to capture LL-37

    Piotr Kolesinski, Kuei-Chen Wang ... Partho Ghosh
    Streptococcus pyogenes M87 protein unfurls its coiled coil to capture and neutralize the human antimicrobial peptide LL-37.
    1. Genetics and Genomics
    2. Microbiology and Infectious Disease

    Rapid adaptation of a complex trait during experimental evolution of Mycobacterium tuberculosis

    Tracy M Smith, Madison A Youngblom ... Caitlin S Pepperell
    Mycobacterium tuberculosis, which causes tuberculosis, can evolve rapidly in response to new environments by mutating genetic regulators that control multiple genes at once.
    1. Microbiology and Infectious Disease

    Lactococcus lactis NCDO2118 exerts visceral antinociceptive properties in rat via GABA production in the gastro-intestinal tract

    Valérie Laroute, Catherine Beaufrand ... Muriel Cocaign-Bousquet
    Generally recognised as safe GABA-producing L. lactis strains could be considered as future therapeutic agents for the management of visceral pain and the anxious profile of IBS patients.
    1. Microbiology and Infectious Disease

    WhyD tailors surface polymers to prevent premature bacteriolysis and direct cell elongation in Streptococcus pneumoniae

    Josué Flores-Kim, Genevieve S Dobihal ... David Z Rudner
    Selective removal of Wall Teichoic Acids from the envelope of Streptococcus pneumoniae prevents bacteriolysis and directs zonal cell wall synthesis.
    1. Evolutionary Biology
    2. Microbiology and Infectious Disease

    Ancestral reconstruction of duplicated signaling proteins reveals the evolution of signaling specificity

    Isabel Nocedal, Michael T Laub
    Ancestral reconstruction of a signaling pathway reveals the mutations responsible for producing specificity of the two paralogous pathways produced by a duplication event.
    1. Microbiology and Infectious Disease

    NAD kinase promotes Staphylococcus aureus pathogenesis by supporting production of virulence factors and protective enzymes

    Clarisse Leseigneur, Laurent Boucontet ... Olivier Dussurget
    Staphylococcus aureus NAD kinase promotes infection by protecting bacteria from host antimicrobial defenses and by supporting production of major virulence factors.
    1. Ecology
    2. Microbiology and Infectious Disease

    Humanization of wildlife gut microbiota in urban environments

    Brian A Dillard, Albert K Chung ... Andrew H Moeller
    Urban wildlife harbor gut bacteria found in humans but missing from rural wildlife, consistent with bacterial transmission from humans to wildlife in cities.
    1. Microbiology and Infectious Disease
    2. Structural Biology and Molecular Biophysics

    Nanoscale resolution of microbial fiber degradation in action

    Meltem Tatli, Sarah Moraïs ... Itzhak Mizrahi
    Phenotypic heterogeneity at the single-cell level of cellulosomal machinery biosynthesis suggests a division-of-labor strategy as revealed by the nanoscale mechanistic and ecological investigation of in situ structure and distribution of cellulosomes on bacteria while interacting with the cellulosic substrate.
    1. Microbiology and Infectious Disease

    Identification of HIV-reservoir cells with reduced susceptibility to antibody-dependent immune response

    Antonio Astorga-Gamaza, Judith Grau-Expósito ... Maria J Buzon
    The expression of CD32 in HIV-reservoir cells prevents the binding of specific anti-HIV antibodies conferring resistance to NK cell-mediated death, and gives the cell the potential to proliferate in the presence of immune complexes.
    1. Microbiology and Infectious Disease
    2. Physics of Living Systems

    Fast bacterial growth reduces antibiotic accumulation and efficacy

    Urszula Łapińska, Margaritis Voliotis ... Stefano Pagliara
    Phenotypic variants that avoid antibiotic accumulation within clonal bacterial populations are a significant contributor to antibiotic treatment failure and can rely on previously unrecognised survival strategies such as fast growth during drug treatment.