Browse our latest Microbiology and Infectious Disease articles

Novel small molecule inhibitors act against Neisseria including multi-drug resistant isolates by uniquely targeting RNR thereby enabling single pathogen therapy whilst sparing the microbiome.

Disruption of disulfide bond formation sensitizes resistant Gram-negative bacteria expressing β-lactamases and mobile colistin resistance enzymes to currently available antibiotics.

RNA m6A level is dually regulated during RV infection and development, METTL3 deficiency in IECs results in increased resistance to rotaviral infection through reduced m6A modificaitons on Irf7.

Rapid evolution and gene conversion of a primate cell surface receptor family blocks recognition by pathogenic bacteria.

The enteric bacterial microbiota stimulates a highly localized interferon-lambda signal within the intestinal epithelium that protects against murine rotavirus infection.

The Spike gene expressed by the vector-based vaccine Vaxzevria bears the risk of cryptic splicing, which in turn may lead to cellular production of soluble, instead of membrane-anchored, Spike protein variants.

A novel dual genome approach that combines genetically diverse mice and a library of bacterial mutants to define the genome-wide host pathogen interactions that drive distinct outcomes to tuberculosis.

Temperature variation caused by heatwaves and diurnal fluctuations has distinct effects on host and pathogen traits at different mean temperatures, leading to large and unexpected differences in disease burden making the impact of global warming on diseases hard to predict.

Lactic acid bacteria engage a hybrid metabolism which blends features of fermentation and respiration when they perform extracellular electron transfer.

The bacterial periplasm must adapt to factors effecting the width of the cell envelope.