Browse our latest Microbiology and Infectious Disease articles

A key target of the HIV-1 Vpr accessory protein is identified, whose depletion causes increased HIV-1gene expression and cell cycle arrest.

A conserved viral protein complex that promotes membrane wrapping of nascent herpesvirus particles shows structural similarity to cellular membrane-remodelling proteins, suggesting functional mimicry.

Analysis of suppressor mutants led to the identification of a novel signalling pathway that regulates peptidoglycan biosynthesis in Gram-positive bacteria.

Time-lapse live cell imaging of single Mycobacterium tuberculosis bacilli growing into small colonies enables their rapid phenotypic characterization including anti-microbial resistance and heteroresistance in clinical isolates.

Genomes take advantage of the gene-duplicating ability of retroelements to birth novel innate immune defense genes.

A new high-throughput method for single-cell RNA-seq in yeast cells shows how stochastic expression of glucose-repressed genes contributes to cell-to-cell differences during adaptation to an environmental change.

eLife has published the following articles on SARS-CoV-2 and COVID-19.

SKAP2 is critical for hematopoietic cell protection against Klebsiella infection in mouse lungs, for full phosphorylation of Src Family Kinases, Syk, and Pyk2, and for Klebsiella-induced reactive oxygen species production.

CD4+ T cells from the female reproductive tract are unusually susceptible to HIV infection and are altered by HIV in ways that promote survival and systemic spread of the virus.

Immune cells in the endometrium are targeted by HIV and re-programmed to allow them to survive and spread the virus throughout the body.