Daniel A Armendariz, Anjana Sundarrajan, Gary C Hon
Continuing advances in functional genomics will enable systematic characterization of how non-coding genetic variation at enhancers impacts developmental diseases.
There was substantial change in primary care activity following the onset of the COVID-19 pandemic in March 2019 as indicated by key measures reflective of clinical activity in general practice but service was largely restored by April 2021.
The BABY algorithm by estimating growth rates of individual cells from time-lapse microscopy images will help characterise the diversity in populations of budding cells, particularly differences in fitness.
Analysis of 458 Kalinago provides new insights into the population's genetic structure, the contribution of Native American ancestry to skin pigmentation, and the identification of a coding variant in OCA2 with an estimated –8 melanin units effect size.
Benjamin Hänisch, Justine Y Hansen ... Sofie Louise Valk
Dimensionality reduction techniques reveal how the organization of neurotransmitter receptor and transporter co-expression in the human brain may bridge the gap between brain structure and function.
Intercellular interactions between fibrocytes and CD8+ T lymphocytes promote inflammation through a pathophysiological positive feedback loop in bronchi of patients with chronic obstructive pulmonary disease (COPD).
A survey of oxygen-dependent enzymes suggests new candidates for oxygen sensors, expanding potential mechanisms underlying hypoxia-related adaptations or diseases in humans.
Imaging of neurons within the hippocampus, a memory region of the brain, reveals how the brain updates memories during different learning conditions compared to when learning is blocked by amnestic drugs.
