Browse our latest research

Page 422 of 1,751
    1. Biochemistry and Chemical Biology
    2. Computational and Systems Biology

    SIMMER employs similarity algorithms to accurately identify human gut microbiome species and enzymes capable of known chemical transformations

    Annamarie E Bustion, Renuka R Nayak ... Katherine S Pollard
    Computational reaction representations and profile hidden Markov model searches of metagenomics databases can be harnessed to accurately predict bacterial species and enzyme sequences responsible for biotransformations in the human gut microbiome.
    1. Cell Biology

    An extracellular vesicle targeting ligand that binds to Arc proteins and facilitates Arc transport in vivo

    Peter H Lee, Michael Anaya ... Kai Zinn
    The cell-surface protein Stranded at second is a targeting ligand for extracellular vesicles that can deliver dArc1 capsids containing dArc1 mRNA to distant cells in vivo.
    1. Biochemistry and Chemical Biology
    2. Cell Biology

    Autophagosome membrane expansion is mediated by the N-terminus and cis-membrane association of human ATG8s

    Wenxin Zhang, Taki Nishimura ... Sharon A Tooze
    cis-membrane insertion of human ATG8 N-terminus facilitates autophagosome membrane expansion independent of autophagic cargo.
    1. Structural Biology and Molecular Biophysics
    2. Immunology and Inflammation

    TCR-pMHC complex formation triggers CD3 dynamics

    Floris J. van Eerden, Aalaa Alrahman Sherif ... Daron M. Standley
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Inadequate
    1. Neuroscience

    Prior information enhances tactile representation in primary somatosensory cortex

    Pegah Kassraian, Finn Rabe ... Nicole Wenderoth
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
    1. Cell Biology
    2. Chromosomes and Gene Expression

    High-precision mapping of nuclear pore-chromatin interactions reveals new principles of genome organization at the nuclear envelope

    Swati Tyagi, Juliana S. Capitanio ... Martin W. Hetzer
    Not revised
    Reviewed Preprint v1
    • Important
    • Compelling
    1. Evolutionary Biology
    2. Genetics and Genomics

    Broad-scale variation in human genetic diversity levels is predicted by purifying selection on coding and non-coding elements

    David A Murphy, Eyal Elyashiv ... Guy Sella
    Background selection is shown to be the dominant mode of linked selection in humans, with marked effects on diversity levels throughout autosomes.
    1. Structural Biology and Molecular Biophysics

    Structural and functional properties of the transporter SLC26A6 reveal mechanism of coupled anion exchange

    David N Tippett, Colum Breen ... Raimund Dutzler
    The structural and functional characterization of SLC26A6 provides greater understanding of coupled versus uncoupled transport processes for the SLC26 transporter family.
    1. Developmental Biology
    2. Microbiology and Infectious Disease

    Intestinal GCN2 controls Drosophila systemic growth in response to Lactiplantibacillus plantarum symbiotic cues encoded by r/tRNA operons

    Théodore Grenier, Jessika Consuegra ... François Leulier
    Bacterial ribosomal and transfer RNAs are symbiotic clues sensed by host general control nonderepressible 2 to support Drosophila systemic growth.
    1. Cell Biology
    2. Computational and Systems Biology

    An in silico FSHD muscle fiber for modeling DUX4 dynamics and predicting the impact of therapy

    Matthew V Cowley, Johanna Pruller ... Christopher RS Banerji
    Mathematical and experimental characterization of DUX4 expression dynamics in facioscapulohumeral muscular dystrophy muscle fibers, provides insights into pathology and open-source tools for in silico investigation of anti-DUX4 therapy.
Newer articles Older articles