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ELYS, a multifunctional protein with critical roles in the cell cycle, is essential for the vigorous proliferation and survival of difficult-to-treat cancers carrying mutations in the KRAS oncogene, making it a compelling target for novel drug treatments.

Human papillomavirus type 8 E6 promotes alternative end joining by compromising non-homologous end joining and homologous recombination.

A cystic fibrosis (CF) lung microbiome-informed in vitro polymicrobial system allows for a mechanistic understanding of community-specific tolerance of Pseudomonas aeruginosa to a front-line CF antimicrobial.

Direct- and indirect pathway neurons of the posterior striatum display divergent in vivo and ex vivo plasticity after fear learning, and differentially modulate defensive behaviors displayed in the presence, and absence of threat-predicting sensory cues.

Integrated single-cell and spatial genomics provides the first molecular map of the human oral mucosa and reveals a novel pro-inflammatory fibroblast involved in disease progression.

The bee gut microbiota contributes to the metabolism of the cyanogenic glycoside amygdalin.

Peroxiredoxin 5 contributes to the maintenance of bone homeostasis by regulating osteoblast differentiation.

Maternal obesity and high-fat diet present metabolic, signaling, and epigenetic impediments to pathogen recognition in fetal innate immune cells that result in a state of immune paralysis during gestation and at birth.

Observations of ant excavation from a confining corral, along with theoretical models and synthetic robot experiments show the emergence of cooperation induced by pheromones in a malleable environment that is moulded by and moulds collective behavior.

A real-time genomic surveillance approach based on mutation analysis of SARS-CoV-2 proteins has enabled a priori prediction of surge in number of COVID19 infection cases, including those already observed in July and September 2022.