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Page 600 of 1,755
    1. Evolutionary Biology

    Fitness consequences of outgroup conflict

    Ines Braga Goncalves, Amy Morris-Drake ... Andrew N Radford
    A detailed discussion of the broad range of immediate, delayed, cumulative, and third-party fitness consequences arising from outgroup conflict showcases the importance of this neglected aspect of sociality as a powerful and widespread evolutionary force.
    1. Neuroscience

    Neural tracking of phrases in spoken language comprehension is automatic and task-dependent

    Sanne ten Oever, Sara Carta ... Andrea E Martin
    The brain’s projection of linguistic knowledge onto speech is reflected by the automatic, reflexive neural tracking of phrases, while the distribution of phrasal-rate tracking and connectivity, particularly the involvement of inferior frontal cortex, is subject to task demands.
    1. Neuroscience

    Biophysical Kv3 channel alterations dampen excitability of cortical PV interneurons and contribute to network hyperexcitability in early Alzheimer’s

    Viktor J Olah, Annie M Goettemoeller ... Matthew JM Rowan
    Electrophysiological and genetic analyses reveal a biophysical mechanism in parvalbumin interneurons, uncoupled from changes in gene expression, resulting in reduced cortical inhibition in early-stage Alzheimer's disease.
    1. Neuroscience

    State-dependent activity dynamics of hypothalamic stress effector neurons

    Aoi Ichiyama, Samuel Mestern ... Wataru Inoue
    Hypothalamic stress effector neurons rapidly change activity patterns via recurrent inhibition, representing state-dependent activity switch between baseline and elevated stress levels.
    1. Cell Biology
    2. Genetics and Genomics

    Phosphoregulation of DSB-1 mediates control of meiotic double-strand break activity

    Heyun Guo, Ericca L Stamper ... Peter M Carlton
    Opposing activities of ATR kinase and PP4 phosphatase balance phosphorylation of the protein DSB-1 to produce sufficient but not excessive amount of DNA double-strand breaks during meiotic prophase in Caenorhabditis elegans.
    1. Ecology
    2. Epidemiology and Global Health

    Predictors of human-infective RNA virus discovery in the United States, China, and Africa, an ecological study

    Feifei Zhang, Margo Chase-Topping ... Mark EJ Woolhouse
    In three different regions including the United States, China, and Africa, virus discoveries were strongly associated with GDP and land use, but were less likely to be associated with climate and biodiversity variables than at a global scale.
    1. Neuroscience

    Human muscle spindles are wired to function as controllable signal-processing devices

    Michael Dimitriou
    By acting as versatile signal-processors that encode flexible coordinate representations, muscle spindles challenge current widely held views concerning the role of proprioceptors and the peripheral nervous system in sensorimotor function.
    1. Developmental Biology
    2. Evolutionary Biology

    Gene expression phylogenies and ancestral transcriptome reconstruction resolves major transitions in the origins of pregnancy

    Katelyn Mika, Camilla M Whittington ... Vincent J Lynch
    Mammals evolved an invasive placenta early in the origins of pregnancy.
    1. Developmental Biology

    Visceral organ morphogenesis via calcium-patterned muscle constrictions

    Noah P Mitchell, Dillon J Cislo ... Sebastian J Streichan
    Whole-organ live imaging and computational analysis reveal a calcium-mediated mechanical program linking gene expression to organ shape.
    1. Neuroscience

    UP-DOWN states and ripples differentially modulate membrane potential dynamics across DG, CA3, and CA1 in awake mice

    Koichiro Kajikawa, Brad K Hulse ... Evgueniy V Lubenov
    The majority of hippocampal neurons in CA3 experience inhibition before and during ripple buildup, while dentate and CA1 cells display depolarizing transients preceding and following ripple onset pointing to a long and orchestrated awake ripple initiation process.