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In a model of human neurulation (neuruloids), YAP is deferentially regulated across ecotodermal lineages, where it contributes to their differentiation and structural organization, and is hyper-active upon HD mutation, contributing to an HD-signature phenotype.

Transiently reprogramming human fibroblasts up to the maturation phase rejuvenates cells according to several aging markers whilst enabling them to return to their original identity.

Transient increases in the hormone testosterone shift behavioral focus by influencing both spatial preference and vocalizations of a monogamous and biparental mouse in the wild.

Cluster analysis reveals convergent T cell clones reacting to tumor antigens, enabling intelligent optimization of cancer immunotherapy.

A calcium-based mechanism of neural recruitment offers a biophysical framework that unifies recent findings on respiratory rhythm generation and pattern formation by the circuitry within the brainstem.

New digital restorations indicate that the structure and function of the shoulder joint were highly variable among Early Cretaceous birds, with such key features as the configuration of the triosseal canal and the nature of scapula-coracoid articulation showing considerable diversity.

Haloperidol comparably affects learning from social and non-social sources when they are the primary source of information but does not affect learning from (social or non-social) secondary sources, providing evidence in support of domain-general neurochemical mechanisms underpinning social learning.

Alternative conformations of membrane protein structures can be predicted to high accuracy with AlphaFold2 by reducing the depth of the multiple sequence alignments used for modeling.

Short-term monocular deprivation effects are widespread in the visual cortex and extend subcortically to the ventral pulvinar, while sparing the dorsal pulvinar and the lateral geniculate nucleus.

compaRe can be used to optimize cytometric high-parameter immunophenotypic characterization of heterogeneous cell populations.