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Combined lineage-tracing strategies, single-cell transcriptomic methods and in situ analyses identified mesodermal bipotent progenitors during craniofacial myogenesis that give rise to myogenic and connective tissues, thus redefining the lineage and evolutionary relationships between muscle and associated stroma.

Bacterial warfare protein colicin E1 opens its hinge to plug antibiotic efflux pump TolC and potentiate antibiotics.

The present findings reveal that subjectively perceived similarities between objects, including those unique to individual observers, are reflected with highest fidelity at the apex of the ventral visual pathway in the medial temporal lobe.

Electrophysiology and optogenetic circuit manipulation in the mouse visual system reveal that corticothalamic feedback and behavioral state both have robust modulatory, yet largely independent influences on thalamic responses to naturalistic movies.

Acetylation of nuclear basket components, following their interaction with accumulating extrachromosomal DNA circles, drives the reorganization of nuclear pore complexes and the loss of cellular viability associated with replicative ageing.

Olfactory neurons of insects, once thought to express only a single type of olfactory receptor, exhibit widespread co-expression of receptors from multiple chemosensory gene families.

Complexin, in conjunction with Synaptotagmin, clamps the SNARE-assembly process under resting conditions and promote vesicle fusion in response to calcium signal.

Tailoring Boolean models to 488 prostate cancer patients and 8 cell lines data allows for the experimentally validated personalisation of drug treatments.

A simple mechanism relying on microtubule rescues occurring at midzone edges allows fission yeast spindles to elongate during anaphase B while maintaining microtubule overlaps, without the need to precisely regulate microtubule growth speed.

Physiological evidence shows that the pupillary response to imagined light can be used to index the strength and vividness of an individual’s visual imagery and as a new tool for confirming aphantasia.