Behavioral and neural data converge in showing that medical experience reduces reactions to others' pain and distrust toward the target affects the processing of his feedback.
Action-value signals previously found in many brain areas can be accounted for neither by concurrent serial correlations in neural activity and action value nor by signals for other decision variables.
Rachel A Johnston, Philippe Vullioud ... Jenny Tung
In cooperatively breeding Damaraland mole-rats, transitioning to 'queen' results in extensive gene regulatory and morphological remodeling, but also costs to skeletal integrity that scale with reproductive investment.
FOXM1 is co-expressed with its bidirectional gene partner RHNO1, and the two genes promote DNA repair, cell growth and survival, and chemotherapy resistance in ovarian cancer.
Biochemical analysis and computational modeling reveal how cells mechanistically control the quality of their proteomes and demonstrate that the precise alignment of subunits in oligomeric complexes can profoundly affect enzymatic properties.
